Difference between revisions of "YJL012C"
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| − | '''Description of YJL012C:''' Vacuolar membrane polyphosphate polymerase; subunit of the vacuolar transporter chaperone (VTC) complex involved in synthesis and transfer of polyP to the vacuole; regulates membrane trafficking; role in non-autophagic vacuolar fusion<ref name='S000040168'>Cohen A, et al. (1999) A novel family of yeast chaperons involved in the distribution of V-ATPase and other membrane proteins. J Biol Chem 274(38):26885-93 {{SGDpaper|S000040168}} PMID 10480897</ref><ref name=' | + | '''Description of YJL012C:''' Vacuolar membrane polyphosphate polymerase; subunit of the vacuolar transporter chaperone (VTC) complex involved in synthesis and transfer of polyP to the vacuole; regulates membrane trafficking; role in non-autophagic vacuolar fusion<ref name='S000040168'>Cohen A, et al. (1999) A novel family of yeast chaperons involved in the distribution of V-ATPase and other membrane proteins. J Biol Chem 274(38):26885-93 {{SGDpaper|S000040168}} PMID 10480897</ref><ref name='S000131552'>Hothorn M, et al. (2009) Catalytic core of a membrane-associated eukaryotic polyphosphate polymerase. Science 324(5926):513-6 {{SGDpaper|S000131552}} PMID 19390046</ref><ref name='S000069426'>Muller O, et al. (2002) The Vtc proteins in vacuole fusion: coupling NSF activity to V(0) trans-complex formation. EMBO J 21(3):259-69 {{SGDpaper|S000069426}} PMID 11823419</ref><ref name='S000074092'>Muller O, et al. (2003) Role of the Vtc proteins in V-ATPase stability and membrane trafficking. J Cell Sci 116(Pt 6):1107-15 {{SGDpaper|S000074092}} PMID 12584253</ref><ref name='S000059109'>Ogawa N, et al. (2000) New components of a system for phosphate accumulation and polyphosphate metabolism in Saccharomyces cerevisiae revealed by genomic expression analysis. Mol Biol Cell 11(12):4309-21 {{SGDpaper|S000059109}} PMID 11102525</ref><ref name='S000123834'>Uttenweiler A, et al. (2007) The vacuolar transporter chaperone (VTC) complex is required for microautophagy. Mol Biol Cell 18(1):166-75 |
{{SGDpaper|S000123834}} PMID 17079729</ref> | {{SGDpaper|S000123834}} PMID 17079729</ref> | ||
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Revision as of 14:05, 25 February 2010
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| Systematic name | YJL012C |
| Gene name | VTC4 |
| Aliases | PHM3, YJL012C-A |
| Feature type | ORF, Verified |
| Coordinates | Chr X:413392..411227 |
| Primary SGDID | S000003549 |
Description of YJL012C: Vacuolar membrane polyphosphate polymerase; subunit of the vacuolar transporter chaperone (VTC) complex involved in synthesis and transfer of polyP to the vacuole; regulates membrane trafficking; role in non-autophagic vacuolar fusion[1][2][3][4][5][6]
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Contents
Community Commentary
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DNA and RNA Details
Other DNA and RNA Details
Other Topic: expression
Specifically higher expression in phosphorus limited chemostat cultures versus phosphorus excess. [7] [8]
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References
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- ↑ Cohen A, et al. (1999) A novel family of yeast chaperons involved in the distribution of V-ATPase and other membrane proteins. J Biol Chem 274(38):26885-93 SGD PMID 10480897
- ↑ Hothorn M, et al. (2009) Catalytic core of a membrane-associated eukaryotic polyphosphate polymerase. Science 324(5926):513-6 SGD PMID 19390046
- ↑ Muller O, et al. (2002) The Vtc proteins in vacuole fusion: coupling NSF activity to V(0) trans-complex formation. EMBO J 21(3):259-69 SGD PMID 11823419
- ↑ Muller O, et al. (2003) Role of the Vtc proteins in V-ATPase stability and membrane trafficking. J Cell Sci 116(Pt 6):1107-15 SGD PMID 12584253
- ↑ Ogawa N, et al. (2000) New components of a system for phosphate accumulation and polyphosphate metabolism in Saccharomyces cerevisiae revealed by genomic expression analysis. Mol Biol Cell 11(12):4309-21 SGD PMID 11102525
- ↑ Uttenweiler A, et al. (2007) The vacuolar transporter chaperone (VTC) complex is required for microautophagy. Mol Biol Cell 18(1):166-75 SGD PMID 17079729
- ↑ Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 SGD PMID 12414795
- ↑ submitted by Viktor Boer on 2003-07-25
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