Difference between revisions of "YGR202C"
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| − | '''Description of YGR202C:''' Cholinephosphate cytidylyltransferase, also known as CTP:phosphocholine cytidylyltransferase, rate-determining enzyme of the CDP-choline pathway for phosphatidylcholine synthesis, inhibited by Sec14p, activated upon lipid-binding<ref name='S000045374'>Skinner HB, et al. (1995) The Saccharomyces cerevisiae phosphatidylinositol-transfer protein effects a ligand-dependent inhibition of choline-phosphate cytidylyltransferase activity. Proc Natl Acad Sci U S A 92(1):112-6 {{SGDpaper|S000045374}} PMID 7816798</ref><ref name='S000051159'>Sreenivas A, et al. (1998) A role for phospholipase D (Pld1p) in growth, secretion, and regulation of membrane lipid synthesis in yeast. J Biol Chem 273(27):16635-8 {{SGDpaper|S000051159}} PMID 9642212</ref><ref name='S000056938'>Tsukagoshi Y, et al. (1987) Molecular cloning and characterization of the gene encoding cholinephosphate cytidylyltransferase in Saccharomyces cerevisiae. Eur J Biochem 169(3):477-86 {{SGDpaper|S000056938}} PMID 2826147 | + | '''Description of YGR202C:''' Cholinephosphate cytidylyltransferase, also known as CTP:phosphocholine cytidylyltransferase, rate-determining enzyme of the CDP-choline pathway for phosphatidylcholine synthesis, inhibited by Sec14p, activated upon lipid-binding<ref name='S000059477'>Dowd SR, et al. (2001) Turnover of phosphatidylcholine in Saccharomyces cerevisiae. The role of the CDP-choline pathway. J Biol Chem 276(6):3756-63 {{SGDpaper|S000059477}} PMID 11078727</ref><ref name='S000064321'>Friesen JA, et al. (2001) Purification and kinetic characterization of CTP:phosphocholine cytidylyltransferase from Saccharomyces cerevisiae. Protein Expr Purif 21(1):141-8 {{SGDpaper|S000064321}} PMID 11162399</ref><ref name='S000045374'>Skinner HB, et al. (1995) The Saccharomyces cerevisiae phosphatidylinositol-transfer protein effects a ligand-dependent inhibition of choline-phosphate cytidylyltransferase activity. Proc Natl Acad Sci U S A 92(1):112-6 {{SGDpaper|S000045374}} PMID 7816798</ref><ref name='S000051159'>Sreenivas A, et al. (1998) A role for phospholipase D (Pld1p) in growth, secretion, and regulation of membrane lipid synthesis in yeast. J Biol Chem 273(27):16635-8 {{SGDpaper|S000051159}} PMID 9642212</ref><ref name='S000056938'>Tsukagoshi Y, et al. (1987) Molecular cloning and characterization of the gene encoding cholinephosphate cytidylyltransferase in Saccharomyces cerevisiae. Eur J Biochem 169(3):477-86 |
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Revision as of 13:05, 25 February 2010
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| Systematic name | YGR202C |
| Gene name | PCT1 |
| Aliases | BSR2, CCT1 |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:904753..903479 |
| Primary SGDID | S000003434 |
Description of YGR202C: Cholinephosphate cytidylyltransferase, also known as CTP:phosphocholine cytidylyltransferase, rate-determining enzyme of the CDP-choline pathway for phosphatidylcholine synthesis, inhibited by Sec14p, activated upon lipid-binding[1][2][3][4][5]
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References
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- ↑ Dowd SR, et al. (2001) Turnover of phosphatidylcholine in Saccharomyces cerevisiae. The role of the CDP-choline pathway. J Biol Chem 276(6):3756-63 SGD PMID 11078727
- ↑ Friesen JA, et al. (2001) Purification and kinetic characterization of CTP:phosphocholine cytidylyltransferase from Saccharomyces cerevisiae. Protein Expr Purif 21(1):141-8 SGD PMID 11162399
- ↑ Skinner HB, et al. (1995) The Saccharomyces cerevisiae phosphatidylinositol-transfer protein effects a ligand-dependent inhibition of choline-phosphate cytidylyltransferase activity. Proc Natl Acad Sci U S A 92(1):112-6 SGD PMID 7816798
- ↑ Sreenivas A, et al. (1998) A role for phospholipase D (Pld1p) in growth, secretion, and regulation of membrane lipid synthesis in yeast. J Biol Chem 273(27):16635-8 SGD PMID 9642212
- ↑ Tsukagoshi Y, et al. (1987) Molecular cloning and characterization of the gene encoding cholinephosphate cytidylyltransferase in Saccharomyces cerevisiae. Eur J Biochem 169(3):477-86 SGD PMID 2826147
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