Difference between revisions of "YGL119W"

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'''Description of YGL119W:''' Protein required for ubiquinone (coenzyme Q) biosynthesis and for respiratory growth; exhibits genetic interaction with COQ9, suggesting a common function; similar to prokaryotic proteins involved in early steps of ubiquinone biosynthesis<ref name='S000039872'>Poon WW, et al. (2000) Identification of Escherichia coli ubiB, a gene required for the first monooxygenase step in ubiquinone biosynthesis. J Bacteriol 182(18):5139-46 {{SGDpaper|S000039872}} PMID 10960098</ref><ref name='S000048591'>Bousquet I, et al. (1991) ABC1, a novel yeast nuclear gene has a dual function in mitochondria: it suppresses a cytochrome b mRNA translation defect and is essential for the electron transfer in the bc 1 complex. EMBO J 10(8):2023-31 {{SGDpaper|S000048591}} PMID 1648478</ref><ref name='S000060371'>Do TQ, et al. (2001) A defect in coenzyme Q biosynthesis is responsible for the respiratory deficiency in Saccharomyces cerevisiae abc1 mutants. J Biol Chem 276(21):18161-8 {{SGDpaper|S000060371}} PMID 11279158</ref><ref name='S000082316'>Johnson A, et al. (2005) COQ9, a new gene required for the biosynthesis of coenzyme Q in Saccharomyces cerevisiae. J Biol Chem 280(36):31397-404
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'''Description of YGL119W:''' Protein required for ubiquinone (coenzyme Q) biosynthesis and for respiratory growth; exhibits genetic interaction with COQ9, suggesting a common function; similar to prokaryotic proteins involved in early steps of ubiquinone biosynthesis<ref name='S000048591'>Bousquet I, et al. (1991) ABC1, a novel yeast nuclear gene has a dual function in mitochondria: it suppresses a cytochrome b mRNA translation defect and is essential for the electron transfer in the bc 1 complex. EMBO J 10(8):2023-31 {{SGDpaper|S000048591}} PMID 1648478</ref><ref name='S000060371'>Do TQ, et al. (2001) A defect in coenzyme Q biosynthesis is responsible for the respiratory deficiency in Saccharomyces cerevisiae abc1 mutants. J Biol Chem 276(21):18161-8 {{SGDpaper|S000060371}} PMID 11279158</ref><ref name='S000082316'>Johnson A, et al. (2005) COQ9, a new gene required for the biosynthesis of coenzyme Q in Saccharomyces cerevisiae. J Biol Chem 280(36):31397-404 {{SGDpaper|S000082316}} PMID 16027161</ref><ref name='S000039872'>Poon WW, et al. (2000) Identification of Escherichia coli ubiB, a gene required for the first monooxygenase step in ubiquinone biosynthesis. J Bacteriol 182(18):5139-46
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  {{SGDpaper|S000039872}} PMID 10960098</ref>
 
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Revision as of 13:05, 25 February 2010

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Systematic name YGL119W
Gene name ABC1
Aliases COQ8
Feature type ORF, Verified
Coordinates Chr VII:284448..285953
Primary SGDID S000003087


Description of YGL119W: Protein required for ubiquinone (coenzyme Q) biosynthesis and for respiratory growth; exhibits genetic interaction with COQ9, suggesting a common function; similar to prokaryotic proteins involved in early steps of ubiquinone biosynthesis[1][2][3][4]




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Protein Details

Other Protein Details

Other Topic: Regulated by the diauxic shift (glycerol)

Apart form the overall increase in mitochondrial protein mass after the diauxic shift this protein remains unchanged after the diauxic shift. [5] [6]





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References

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  1. Bousquet I, et al. (1991) ABC1, a novel yeast nuclear gene has a dual function in mitochondria: it suppresses a cytochrome b mRNA translation defect and is essential for the electron transfer in the bc 1 complex. EMBO J 10(8):2023-31 SGD PMID 1648478
  2. Do TQ, et al. (2001) A defect in coenzyme Q biosynthesis is responsible for the respiratory deficiency in Saccharomyces cerevisiae abc1 mutants. J Biol Chem 276(21):18161-8 SGD PMID 11279158
  3. Johnson A, et al. (2005) COQ9, a new gene required for the biosynthesis of coenzyme Q in Saccharomyces cerevisiae. J Biol Chem 280(36):31397-404 SGD PMID 16027161
  4. Poon WW, et al. (2000) Identification of Escherichia coli ubiB, a gene required for the first monooxygenase step in ubiquinone biosynthesis. J Bacteriol 182(18):5139-46 SGD PMID 10960098
  5. Ohlmeier S, et al. (2004) The yeast mitochondrial proteome, a study of fermentative and respiratory growth. J Biol Chem 279(6):3956-79 SGD PMID 14597615
  6. submitted by Steffen Ohlmeier on 2004-04-08

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