Difference between revisions of "YDL209C"

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'''Description of YDL209C:''' Member of the NineTeen Complex (NTC) that contains Prp19p and stabilizes U6 snRNA in catalytic forms of the spliceosome containing U2, U5, and U6 snRNAs; binds directly to U6 snRNA; similar to S. pombe Cwf2<ref name='S000069712'>Ohi MD, et al. (2002) Proteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs. Mol Cell Biol 22(7):2011-24 {{SGDpaper|S000069712}} PMID 11884590</ref><ref name='S000070110'>Ohi MD and Gould KL (2002) Characterization of interactions among the Cef1p-Prp19p-associated splicing complex. RNA 8(6):798-815 {{SGDpaper|S000070110}} PMID 12088152</ref><ref name='S000130294'>McGrail JC, et al. (2009) The RNA binding protein Cwc2 interacts directly with the U6 snRNA to link the nineteen complex to the spliceosome during pre-mRNA splicing. Nucleic Acids Res 37(13):4205-17
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'''Description of YDL209C:''' Member of the NineTeen Complex (NTC) that contains Prp19p and stabilizes U6 snRNA in catalytic forms of the spliceosome containing U2, U5, and U6 snRNAs; binds directly to U6 snRNA; similar to S. pombe Cwf2<ref name='S000130294'>McGrail JC, et al. (2009) The RNA binding protein Cwc2 interacts directly with the U6 snRNA to link the nineteen complex to the spliceosome during pre-mRNA splicing. Nucleic Acids Res 37(13):4205-17 {{SGDpaper|S000130294}} PMID 19435883</ref><ref name='S000070110'>Ohi MD and Gould KL (2002) Characterization of interactions among the Cef1p-Prp19p-associated splicing complex. RNA 8(6):798-815 {{SGDpaper|S000070110}} PMID 12088152</ref><ref name='S000069712'>Ohi MD, et al. (2002) Proteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs. Mol Cell Biol 22(7):2011-24
  {{SGDpaper|S000130294}} PMID 19435883</ref>
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  {{SGDpaper|S000069712}} PMID 11884590</ref>
 
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Revision as of 14:05, 25 February 2010

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Systematic name YDL209C
Gene name CWC2
Aliases NTC40
Feature type ORF, Verified
Coordinates Chr IV:87227..86208
Primary SGDID S000002368


Description of YDL209C: Member of the NineTeen Complex (NTC) that contains Prp19p and stabilizes U6 snRNA in catalytic forms of the spliceosome containing U2, U5, and U6 snRNAs; binds directly to U6 snRNA; similar to S. pombe Cwf2[1][2][3]




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References

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  1. McGrail JC, et al. (2009) The RNA binding protein Cwc2 interacts directly with the U6 snRNA to link the nineteen complex to the spliceosome during pre-mRNA splicing. Nucleic Acids Res 37(13):4205-17 SGD PMID 19435883
  2. Ohi MD and Gould KL (2002) Characterization of interactions among the Cef1p-Prp19p-associated splicing complex. RNA 8(6):798-815 SGD PMID 12088152
  3. Ohi MD, et al. (2002) Proteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs. Mol Cell Biol 22(7):2011-24 SGD PMID 11884590

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