Difference between revisions of "YKL212W"

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'''Description of YKL212W:''' Phosphatidylinositol phosphate (PtdInsP) phosphatase involved in hydrolysis of PtdIns[4]P; transmembrane protein localizes to ER and Golgi; involved in protein trafficking and processing, secretion, and cell wall maintenance<ref name='S000040606'>Whitters EA, et al. (1993) SAC1p is an integral membrane protein that influences the cellular requirement for phospholipid transfer protein function and inositol in yeast. J Cell Biol 122(1):79-94 {{SGDpaper|S000040606}} PMID 8314848</ref><ref name='S000045780'>Guo S, et al. (1999) SAC1-like domains of yeast SAC1, INP52, and INP53 and of human synaptojanin encode polyphosphoinositide phosphatases. J Biol Chem 274(19):12990-5 {{SGDpaper|S000045780}} PMID 10224048</ref><ref name='S000055623'>Hughes WE, et al. (2000) SAC1 encodes a regulated lipid phosphoinositide phosphatase, defects in which can be suppressed by the homologous Inp52p and Inp53p phosphatases. J Biol Chem 275(2):801-8 {{SGDpaper|S000055623}} PMID 10625610</ref><ref name='S000069028'>Schorr M, et al. (2001) The phosphoinositide phosphatase Sac1p controls trafficking of the yeast Chs3p chitin synthase. Curr Biol 11(18):1421-6
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'''Description of YKL212W:''' Phosphatidylinositol phosphate (PtdInsP) phosphatase involved in hydrolysis of PtdIns[4]P; transmembrane protein localizes to ER and Golgi; involved in protein trafficking and processing, secretion, and cell wall maintenance<ref name='S000045780'>Guo S, et al. (1999) SAC1-like domains of yeast SAC1, INP52, and INP53 and of human synaptojanin encode polyphosphoinositide phosphatases. J Biol Chem 274(19):12990-5 {{SGDpaper|S000045780}} PMID 10224048</ref><ref name='S000055623'>Hughes WE, et al. (2000) SAC1 encodes a regulated lipid phosphoinositide phosphatase, defects in which can be suppressed by the homologous Inp52p and Inp53p phosphatases. J Biol Chem 275(2):801-8 {{SGDpaper|S000055623}} PMID 10625610</ref><ref name='S000069028'>Schorr M, et al. (2001) The phosphoinositide phosphatase Sac1p controls trafficking of the yeast Chs3p chitin synthase. Curr Biol 11(18):1421-6 {{SGDpaper|S000069028}} PMID 11566100</ref><ref name='S000040606'>Whitters EA, et al. (1993) SAC1p is an integral membrane protein that influences the cellular requirement for phospholipid transfer protein function and inositol in yeast. J Cell Biol 122(1):79-94
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  {{SGDpaper|S000040606}} PMID 8314848</ref>
 
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Revision as of 14:05, 25 February 2010

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Systematic name YKL212W
Gene name SAC1
Aliases RSD1
Feature type ORF, Verified
Coordinates Chr XI:34544..36415
Primary SGDID S000001695


Description of YKL212W: Phosphatidylinositol phosphate (PtdInsP) phosphatase involved in hydrolysis of PtdIns[4]P; transmembrane protein localizes to ER and Golgi; involved in protein trafficking and processing, secretion, and cell wall maintenance[1][2][3][4]




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References

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  1. Guo S, et al. (1999) SAC1-like domains of yeast SAC1, INP52, and INP53 and of human synaptojanin encode polyphosphoinositide phosphatases. J Biol Chem 274(19):12990-5 SGD PMID 10224048
  2. Hughes WE, et al. (2000) SAC1 encodes a regulated lipid phosphoinositide phosphatase, defects in which can be suppressed by the homologous Inp52p and Inp53p phosphatases. J Biol Chem 275(2):801-8 SGD PMID 10625610
  3. Schorr M, et al. (2001) The phosphoinositide phosphatase Sac1p controls trafficking of the yeast Chs3p chitin synthase. Curr Biol 11(18):1421-6 SGD PMID 11566100
  4. Whitters EA, et al. (1993) SAC1p is an integral membrane protein that influences the cellular requirement for phospholipid transfer protein function and inositol in yeast. J Cell Biol 122(1):79-94 SGD PMID 8314848

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