Difference between revisions of "YKL019W"
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| − | '''Description of YKL019W:''' Alpha subunit of both the farnesyltransferase and type I geranylgeranyltransferase that catalyze prenylation of proteins containing a CAAX consensus motif; essential protein required for membrane localization of Ras proteins and a-factor | + | '''Description of YKL019W:''' Alpha subunit of both the farnesyltransferase and type I geranylgeranyltransferase that catalyze prenylation of proteins containing a CAAX consensus motif; essential protein required for membrane localization of Ras proteins and a-factor<ref name='S000048882'>Gomez R, et al. (1993) Purified yeast protein farnesyltransferase is structurally and functionally similar to its mammalian counterpart. Biochem J 289 ( Pt 1)():25-31 {{SGDpaper|S000048882}} PMID 8424764</ref><ref name='S000050062'>He B, et al. (1991) RAM2, an essential gene of yeast, and RAM1 encode the two polypeptide components of the farnesyltransferase that prenylates a-factor and Ras proteins. Proc Natl Acad Sci U S A 88(24):11373-7 {{SGDpaper|S000050062}} PMID 1763050</ref><ref name='S000052892'>Kohl NE, et al. (1991) Structural homology among mammalian and Saccharomyces cerevisiae isoprenyl-protein transferases. J Biol Chem 266(28):18884-8 {{SGDpaper|S000052892}} PMID 1918005</ref><ref name='S000044942'>Mayer ML, et al. (1992) CDC43 and RAM2 encode the polypeptide subunits of a yeast type I protein geranylgeranyltransferase. J Biol Chem 267(29):20589-93 |
| − | {{SGDpaper| | + | {{SGDpaper|S000044942}} PMID 1400380</ref> |
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Revision as of 13:05, 25 February 2010
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| Systematic name | YKL019W |
| Gene name | RAM2 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XI:402211..403161 |
| Primary SGDID | S000001502 |
Description of YKL019W: Alpha subunit of both the farnesyltransferase and type I geranylgeranyltransferase that catalyze prenylation of proteins containing a CAAX consensus motif; essential protein required for membrane localization of Ras proteins and a-factor[1][2][3][4]
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References
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- ↑ Gomez R, et al. (1993) Purified yeast protein farnesyltransferase is structurally and functionally similar to its mammalian counterpart. Biochem J 289 ( Pt 1)():25-31 SGD PMID 8424764
- ↑ He B, et al. (1991) RAM2, an essential gene of yeast, and RAM1 encode the two polypeptide components of the farnesyltransferase that prenylates a-factor and Ras proteins. Proc Natl Acad Sci U S A 88(24):11373-7 SGD PMID 1763050
- ↑ Kohl NE, et al. (1991) Structural homology among mammalian and Saccharomyces cerevisiae isoprenyl-protein transferases. J Biol Chem 266(28):18884-8 SGD PMID 1918005
- ↑ Mayer ML, et al. (1992) CDC43 and RAM2 encode the polypeptide subunits of a yeast type I protein geranylgeranyltransferase. J Biol Chem 267(29):20589-93 SGD PMID 1400380
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