Difference between revisions of "YHR098C"

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'''Description of YHR098C:''' Component of the Sec23p-Sfb3p heterodimer of the COPII vesicle coat, required for cargo selection during vesicle formation in ER to Golgi transport; homologous to Sec24p and Sfb2p<ref name='S000049853'>Roberg KJ, et al. (1999) LST1 is a SEC24 homologue used for selective export of the plasma membrane ATPase from the endoplasmic reticulum. J Cell Biol 145(4):659-72 {{SGDpaper|S000049853}} PMID 10330397</ref><ref name='S000059360'>Shimoni Y, et al. (2000) Lst1p and Sec24p cooperate in sorting of the plasma membrane ATPase into COPII vesicles in Saccharomyces cerevisiae. J Cell Biol 151(5):973-84 {{SGDpaper|S000059360}} PMID 11086000</ref><ref name='S000071975'>Miller E, et al. (2002) Cargo selection into COPII vesicles is driven by the Sec24p subunit. EMBO J 21(22):6105-13 {{SGDpaper|S000071975}} PMID 12426382</ref><ref name='S000074170'>Miller EA, et al. (2003) Multiple cargo binding sites on the COPII subunit Sec24p ensure capture of diverse membrane proteins into transport vesicles. Cell 114(4):497-509
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'''Description of YHR098C:''' Component of the Sec23p-Sfb3p heterodimer of the COPII vesicle coat, required for cargo selection during vesicle formation in ER to Golgi transport; homologous to Sec24p and Sfb2p<ref name='S000071975'>Miller E, et al. (2002) Cargo selection into COPII vesicles is driven by the Sec24p subunit. EMBO J 21(22):6105-13 {{SGDpaper|S000071975}} PMID 12426382</ref><ref name='S000074170'>Miller EA, et al. (2003) Multiple cargo binding sites on the COPII subunit Sec24p ensure capture of diverse membrane proteins into transport vesicles. Cell 114(4):497-509 {{SGDpaper|S000074170}} PMID 12941277</ref><ref name='S000049853'>Roberg KJ, et al. (1999) LST1 is a SEC24 homologue used for selective export of the plasma membrane ATPase from the endoplasmic reticulum. J Cell Biol 145(4):659-72 {{SGDpaper|S000049853}} PMID 10330397</ref><ref name='S000059360'>Shimoni Y, et al. (2000) Lst1p and Sec24p cooperate in sorting of the plasma membrane ATPase into COPII vesicles in Saccharomyces cerevisiae. J Cell Biol 151(5):973-84
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  {{SGDpaper|S000059360}} PMID 11086000</ref>
 
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Revision as of 14:05, 25 February 2010

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Systematic name YHR098C
Gene name SFB3
Aliases LST1
Feature type ORF, Verified
Coordinates Chr VIII:301937..299148
Primary SGDID S000001140


Description of YHR098C: Component of the Sec23p-Sfb3p heterodimer of the COPII vesicle coat, required for cargo selection during vesicle formation in ER to Golgi transport; homologous to Sec24p and Sfb2p[1][2][3][4]




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Protein Details

Protein Modification

Modification(s): Phosphorylation

Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [5] [6]





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References

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  1. Jump up Miller E, et al. (2002) Cargo selection into COPII vesicles is driven by the Sec24p subunit. EMBO J 21(22):6105-13 SGD PMID 12426382
  2. Jump up Miller EA, et al. (2003) Multiple cargo binding sites on the COPII subunit Sec24p ensure capture of diverse membrane proteins into transport vesicles. Cell 114(4):497-509 SGD PMID 12941277
  3. Jump up Roberg KJ, et al. (1999) LST1 is a SEC24 homologue used for selective export of the plasma membrane ATPase from the endoplasmic reticulum. J Cell Biol 145(4):659-72 SGD PMID 10330397
  4. Jump up Shimoni Y, et al. (2000) Lst1p and Sec24p cooperate in sorting of the plasma membrane ATPase into COPII vesicles in Saccharomyces cerevisiae. J Cell Biol 151(5):973-84 SGD PMID 11086000
  5. Jump up Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
  6. Jump up submitted by Jeff Ubersax on 2004-01-27

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