Difference between revisions of "YNR026C"
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| − | '''Description of YNR026C:''' Guanine nucleotide exchange factor (GEF); | + | '''Description of YNR026C:''' Guanine nucleotide exchange factor (GEF), activates Sar1p by catalyzing the exchange of GDP for GTP; required for the initiation of COPII vesicle formation in ER to Golgi transport; glycosylated integral membrane protein of the ER<ref name='S000048204'>Barlowe C and Schekman R (1993) SEC12 encodes a guanine-nucleotide-exchange factor essential for transport vesicle budding from the ER. Nature 365(6444):347-9 {{SGDpaper|S000048204}} PMID 8377826</ref><ref name='S000053172'>d'Enfert C, et al. (1991) Sec12p-dependent membrane binding of the small GTP-binding protein Sar1p promotes formation of transport vesicles from the ER. J Cell Biol 114(4):663-70 |
{{SGDpaper|S000053172}} PMID 1907973</ref> | {{SGDpaper|S000053172}} PMID 1907973</ref> | ||
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Revision as of 13:05, 8 January 2010
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| Systematic name | YNR026C |
| Gene name | SEC12 |
| Aliases | SED2 |
| Feature type | ORF, Verified |
| Coordinates | Chr XIV:674692..673277 |
| Primary SGDID | S000005309 |
Description of YNR026C: Guanine nucleotide exchange factor (GEF), activates Sar1p by catalyzing the exchange of GDP for GTP; required for the initiation of COPII vesicle formation in ER to Golgi transport; glycosylated integral membrane protein of the ER[1][2]
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References
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- ↑ Barlowe C and Schekman R (1993) SEC12 encodes a guanine-nucleotide-exchange factor essential for transport vesicle budding from the ER. Nature 365(6444):347-9 SGD PMID 8377826
- ↑ d'Enfert C, et al. (1991) Sec12p-dependent membrane binding of the small GTP-binding protein Sar1p promotes formation of transport vesicles from the ER. J Cell Biol 114(4):663-70 SGD PMID 1907973
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