Difference between revisions of "YBR034C"
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| − | '''Description of YBR034C:''' Nuclear SAM-dependent mono- and asymmetric arginine dimethylating methyltransferase that modifies hnRNPs, including Npl3p and Hrp1p, thus facilitating nuclear export of these proteins; | + | '''Description of YBR034C:''' Nuclear SAM-dependent mono- and asymmetric arginine dimethylating methyltransferase that modifies hnRNPs, including Npl3p and Hrp1p, thus facilitating nuclear export of these proteins; also methylates ribosomal protein Rps2p<ref name='S000041792'>Henry MF and Silver PA (1996) A novel methyltransferase (Hmt1p) modifies poly(A)+-RNA-binding proteins. Mol Cell Biol 16(7):3668-78 {{SGDpaper|S000041792}} PMID 8668183</ref><ref name='S000052349'>Shen EC, et al. (1998) Arginine methylation facilitates the nuclear export of hnRNP proteins. Genes Dev 12(5):679-91 {{SGDpaper|S000052349}} PMID 9499403</ref><ref name='S000054888'>Gary JD, et al. (1996) The predominant protein-arginine methyltransferase from Saccharomyces cerevisiae. J Biol Chem 271(21):12585-94 {{SGDpaper|S000054888}} PMID 8647869</ref><ref name='S000132571'>Lipson RS, et al. (2009) Rmt1 catalyzes zinc-finger independent arginine methylation of the small ribosomal protein Rps2 in Saccharomyces cerevisiae. Biochem Biophys Res Commun () |
| − | {{SGDpaper| | + | {{SGDpaper|S000132571}} PMID 20035717</ref> |
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Revision as of 13:05, 3 January 2010
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| Systematic name | YBR034C |
| Gene name | HMT1 |
| Aliases | HCP1, ODP1, RMT1 |
| Feature type | ORF, Verified |
| Coordinates | Chr II:305976..304930 |
| Primary SGDID | S000000238 |
Description of YBR034C: Nuclear SAM-dependent mono- and asymmetric arginine dimethylating methyltransferase that modifies hnRNPs, including Npl3p and Hrp1p, thus facilitating nuclear export of these proteins; also methylates ribosomal protein Rps2p[1][2][3][4]
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References
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- ↑ Henry MF and Silver PA (1996) A novel methyltransferase (Hmt1p) modifies poly(A)+-RNA-binding proteins. Mol Cell Biol 16(7):3668-78 SGD PMID 8668183
- ↑ Shen EC, et al. (1998) Arginine methylation facilitates the nuclear export of hnRNP proteins. Genes Dev 12(5):679-91 SGD PMID 9499403
- ↑ Gary JD, et al. (1996) The predominant protein-arginine methyltransferase from Saccharomyces cerevisiae. J Biol Chem 271(21):12585-94 SGD PMID 8647869
- ↑ Lipson RS, et al. (2009) Rmt1 catalyzes zinc-finger independent arginine methylation of the small ribosomal protein Rps2 in Saccharomyces cerevisiae. Biochem Biophys Res Commun () SGD PMID 20035717
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