Difference between revisions of "YGR216C"
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− | '''Description of YGR216C:''' Membrane protein involved in the synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the first intermediate in the synthesis of glycosylphosphatidylinositol (GPI) anchors; human and mouse GPI1p are functional homologs<ref name='S000045515'>Tiede A, et al. (1998) Human and mouse Gpi1p homologues restore glycosylphosphatidylinositol membrane anchor biosynthesis in yeast mutants. Biochem J 334 ( Pt 3):609-16 {{SGDpaper|S000045515}} PMID 9729469</ref><ref name='S000046763'>Leidich SD and Orlean P (1996) Gpi1, a Saccharomyces cerevisiae protein that participates in the first step in glycosylphosphatidylinositol anchor synthesis. J Biol Chem 271(44):27829-37 {{SGDpaper|S000046763}} PMID 8910381</ref><ref name='S000055267'>Leidich SD, et al. (1994) A conditionally lethal yeast mutant blocked at the first step in glycosyl phosphatidylinositol anchor synthesis. J Biol Chem 269(14):10193-6 {{SGDpaper|S000055267}} PMID 8144596</ref><ref name='S000058280'>Watanabe R, et al. (1998) The first step of glycosylphosphatidylinositol biosynthesis is mediated by a complex of PIG-A, PIG-H, PIG-C and GPI1. EMBO J 17(4):877-85 | + | '''Description of YGR216C:''' Membrane protein involved in the synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the first intermediate in the synthesis of glycosylphosphatidylinositol (GPI) anchors; human and mouse GPI1p are functional homologs<ref name='S000045515'>Tiede A, et al. (1998) Human and mouse Gpi1p homologues restore glycosylphosphatidylinositol membrane anchor biosynthesis in yeast mutants. Biochem J 334 ( Pt 3)():609-16 {{SGDpaper|S000045515}} PMID 9729469</ref><ref name='S000046763'>Leidich SD and Orlean P (1996) Gpi1, a Saccharomyces cerevisiae protein that participates in the first step in glycosylphosphatidylinositol anchor synthesis. J Biol Chem 271(44):27829-37 {{SGDpaper|S000046763}} PMID 8910381</ref><ref name='S000055267'>Leidich SD, et al. (1994) A conditionally lethal yeast mutant blocked at the first step in glycosyl phosphatidylinositol anchor synthesis. J Biol Chem 269(14):10193-6 {{SGDpaper|S000055267}} PMID 8144596</ref><ref name='S000058280'>Watanabe R, et al. (1998) The first step of glycosylphosphatidylinositol biosynthesis is mediated by a complex of PIG-A, PIG-H, PIG-C and GPI1. EMBO J 17(4):877-85 |
{{SGDpaper|S000058280}} PMID 9463366</ref> | {{SGDpaper|S000058280}} PMID 9463366</ref> | ||
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Revision as of 13:05, 18 December 2009
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Systematic name | YGR216C |
Gene name | GPI1 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr VII:924467..922638 |
Primary SGDID | S000003448 |
Description of YGR216C: Membrane protein involved in the synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the first intermediate in the synthesis of glycosylphosphatidylinositol (GPI) anchors; human and mouse GPI1p are functional homologs[1][2][3][4]
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References
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- ↑ Tiede A, et al. (1998) Human and mouse Gpi1p homologues restore glycosylphosphatidylinositol membrane anchor biosynthesis in yeast mutants. Biochem J 334 ( Pt 3)():609-16 SGD PMID 9729469
- ↑ Leidich SD and Orlean P (1996) Gpi1, a Saccharomyces cerevisiae protein that participates in the first step in glycosylphosphatidylinositol anchor synthesis. J Biol Chem 271(44):27829-37 SGD PMID 8910381
- ↑ Leidich SD, et al. (1994) A conditionally lethal yeast mutant blocked at the first step in glycosyl phosphatidylinositol anchor synthesis. J Biol Chem 269(14):10193-6 SGD PMID 8144596
- ↑ Watanabe R, et al. (1998) The first step of glycosylphosphatidylinositol biosynthesis is mediated by a complex of PIG-A, PIG-H, PIG-C and GPI1. EMBO J 17(4):877-85 SGD PMID 9463366
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