Difference between revisions of "YER078C"
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| − | '''Description of YER078C:''' Mitochondrial | + | '''Description of YER078C:''' Mitochondrial aminopeptidase; cleaves the N termini of at least 38 imported proteins after cleavage by the mitochondrial processing peptidase (MPP), thereby increasing their stability; member of the aminopeptidase P family<ref name='S000117178'>Reinders J, et al. (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J Proteome Res 5(7):1543-54 {{SGDpaper|S000117178}} PMID 16823961</ref><ref name='S000074185'>Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 {{SGDpaper|S000074185}} PMID 14562095</ref><ref name='S000132064'>Vogtle FN, et al. (2009) Global analysis of the mitochondrial N-proteome identifies a processing peptidase critical for protein stability. Cell 139(2):428-39 {{SGDpaper|S000132064}} PMID 19837041</ref><ref name='S000131441'>Naamati A, et al. (2009) Dual targeting of Nfs1 and discovery of its novel processing enzyme, Icp55. J Biol Chem 284(44):30200-8 |
{{SGDpaper|S000131441}} PMID 19720832</ref> | {{SGDpaper|S000131441}} PMID 19720832</ref> | ||
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Revision as of 13:05, 14 December 2009
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| Systematic name | YER078C |
| Gene name | ICP55 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr V:318338..316803 |
| Primary SGDID | S000000880 |
Description of YER078C: Mitochondrial aminopeptidase; cleaves the N termini of at least 38 imported proteins after cleavage by the mitochondrial processing peptidase (MPP), thereby increasing their stability; member of the aminopeptidase P family[1][2][3][4]
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Community Commentary
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Protein Details
Protein Localization
Protein identified in a purified mitochondrial extract. [5] [6]
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References
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- ↑ Reinders J, et al. (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J Proteome Res 5(7):1543-54 SGD PMID 16823961
- ↑ Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD PMID 14562095
- ↑ Vogtle FN, et al. (2009) Global analysis of the mitochondrial N-proteome identifies a processing peptidase critical for protein stability. Cell 139(2):428-39 SGD PMID 19837041
- ↑ Naamati A, et al. (2009) Dual targeting of Nfs1 and discovery of its novel processing enzyme, Icp55. J Biol Chem 284(44):30200-8 SGD PMID 19720832
- ↑ Ohlmeier S, et al. (2004) The yeast mitochondrial proteome, a study of fermentative and respiratory growth. J Biol Chem 279(6):3956-79 SGD PMID 14597615
- ↑ submitted by Steffen Ohlmeier on 2004-04-08
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