Difference between revisions of "YML061C"

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'''Description of YML061C:''' DNA helicase involved in telomere formation and elongation; acts as a catalytic inhibitor of telomerase; also plays a role in repair and recombination of mitochondrial DNA<ref name='S000041506'>Ivessa AS, et al. (2000) The Saccharomyces Pif1p DNA helicase and the highly related Rrm3p have opposite effects on replication fork progression in ribosomal DNA. Cell 100(4):479-89 {{SGDpaper|S000041506}} PMID 10693764</ref><ref name='S000046554'>Foury F and Lahaye A (1987) Cloning and sequencing of the PIF gene involved in repair and recombination of yeast mitochondrial DNA. EMBO J 6(5):1441-9 {{SGDpaper|S000046554}} PMID 3038524</ref><ref name='S000055909'>Zhou J, et al. (2000) Pif1p helicase, a catalytic inhibitor of telomerase in yeast. Science 289(5480):771-4
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'''Description of YML061C:''' DNA helicase; exists in two forms; the nuclear form is involved in telomere formation and elongation; acts as a catalytic inhibitor of telomerase; the mitochondrial form is involved in repair and recombination of mitochondrial DNA<ref name='S000041506'>Ivessa AS, et al. (2000) The Saccharomyces Pif1p DNA helicase and the highly related Rrm3p have opposite effects on replication fork progression in ribosomal DNA. Cell 100(4):479-89 {{SGDpaper|S000041506}} PMID 10693764</ref><ref name='S000046554'>Foury F and Lahaye A (1987) Cloning and sequencing of the PIF gene involved in repair and recombination of yeast mitochondrial DNA. EMBO J 6(5):1441-9 {{SGDpaper|S000046554}} PMID 3038524</ref><ref name='S000055909'>Zhou J, et al. (2000) Pif1p helicase, a catalytic inhibitor of telomerase in yeast. Science 289(5480):771-4 {{SGDpaper|S000055909}} PMID 10926538</ref><ref name='S000123131'>Vega LR, et al. (2007) Sensitivity of yeast strains with long g-tails to levels of telomere-bound telomerase. PLoS Genet 3(6):e105
  {{SGDpaper|S000055909}} PMID 10926538</ref>
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  {{SGDpaper|S000123131}} PMID 17590086</ref>
 
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Revision as of 13:05, 12 November 2009

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Systematic name YML061C
Gene name PIF1
Aliases TST1
Feature type ORF, Verified
Coordinates Chr XIII:151532..148953
Primary SGDID S000004526


Description of YML061C: DNA helicase; exists in two forms; the nuclear form is involved in telomere formation and elongation; acts as a catalytic inhibitor of telomerase; the mitochondrial form is involved in repair and recombination of mitochondrial DNA[1][2][3][4]




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DNA and RNA Details

Other DNA and RNA Details

Other Topic: expression

Specifically lower expression in carbon limited chemostat cultures versus carbon excess. [5] [6]





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References

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  1. Ivessa AS, et al. (2000) The Saccharomyces Pif1p DNA helicase and the highly related Rrm3p have opposite effects on replication fork progression in ribosomal DNA. Cell 100(4):479-89 SGD PMID 10693764
  2. Foury F and Lahaye A (1987) Cloning and sequencing of the PIF gene involved in repair and recombination of yeast mitochondrial DNA. EMBO J 6(5):1441-9 SGD PMID 3038524
  3. Zhou J, et al. (2000) Pif1p helicase, a catalytic inhibitor of telomerase in yeast. Science 289(5480):771-4 SGD PMID 10926538
  4. Vega LR, et al. (2007) Sensitivity of yeast strains with long g-tails to levels of telomere-bound telomerase. PLoS Genet 3(6):e105 SGD PMID 17590086
  5. Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 SGD PMID 12414795
  6. submitted by Viktor Boer on 2003-07-25

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