Difference between revisions of "YBR038W"
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| − | '''Description of YBR038W:''' Chitin synthase II; catalyzes transfer of N-acetylglucosamine (GlcNAc) to chitin upon activation of zymogenic form; required for chitin synthesis in the primary septum during cytokinesis; localization regulated by Cdk1p during mitosis<ref name='S000050095'>Shaw JA, et al. (1991) The function of chitin synthases 2 and 3 in the Saccharomyces cerevisiae cell cycle. J Cell Biol 114(1):111-23 {{SGDpaper|S000050095}} PMID 2050738</ref><ref name='S000057374'>Cid VJ, et al. (1995) Molecular basis of cell integrity and morphogenesis in Saccharomyces cerevisiae. Microbiol Rev 59(3):345-86 {{SGDpaper|S000057374}} PMID 7565410</ref><ref name='S000069165'>Schmidt M, et al. (2002) In budding yeast, contraction of the actomyosin ring and formation of the primary septum at cytokinesis depend on each other. J Cell Sci 115(Pt 2):293-302 {{SGDpaper|S000069165}} PMID 11839781</ref><ref name='S000131348'>Teh EM, et al. (2009) Retention of Chs2p in the ER requires N-terminal CDK1-phosphorylation sites. Cell Cycle 8(18) | + | '''Description of YBR038W:''' Chitin synthase II; catalyzes transfer of N-acetylglucosamine (GlcNAc) to chitin upon activation of zymogenic form; required for chitin synthesis in the primary septum during cytokinesis; localization regulated by Cdk1p during mitosis<ref name='S000050095'>Shaw JA, et al. (1991) The function of chitin synthases 2 and 3 in the Saccharomyces cerevisiae cell cycle. J Cell Biol 114(1):111-23 {{SGDpaper|S000050095}} PMID 2050738</ref><ref name='S000057374'>Cid VJ, et al. (1995) Molecular basis of cell integrity and morphogenesis in Saccharomyces cerevisiae. Microbiol Rev 59(3):345-86 {{SGDpaper|S000057374}} PMID 7565410</ref><ref name='S000069165'>Schmidt M, et al. (2002) In budding yeast, contraction of the actomyosin ring and formation of the primary septum at cytokinesis depend on each other. J Cell Sci 115(Pt 2):293-302 {{SGDpaper|S000069165}} PMID 11839781</ref><ref name='S000131348'>Teh EM, et al. (2009) Retention of Chs2p in the ER requires N-terminal CDK1-phosphorylation sites. Cell Cycle 8(18):2964-74 |
{{SGDpaper|S000131348}} PMID 19713768</ref> | {{SGDpaper|S000131348}} PMID 19713768</ref> | ||
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Revision as of 13:05, 12 September 2009
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| Systematic name | YBR038W |
| Gene name | CHS2 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr II:311897..314788 |
| Primary SGDID | S000000242 |
Description of YBR038W: Chitin synthase II; catalyzes transfer of N-acetylglucosamine (GlcNAc) to chitin upon activation of zymogenic form; required for chitin synthesis in the primary septum during cytokinesis; localization regulated by Cdk1p during mitosis[1][2][3][4]
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Protein Details
Protein Modification
Modification(s): Phosphorylation
Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [5] [6]
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References
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- ↑ Shaw JA, et al. (1991) The function of chitin synthases 2 and 3 in the Saccharomyces cerevisiae cell cycle. J Cell Biol 114(1):111-23 SGD PMID 2050738
- ↑ Cid VJ, et al. (1995) Molecular basis of cell integrity and morphogenesis in Saccharomyces cerevisiae. Microbiol Rev 59(3):345-86 SGD PMID 7565410
- ↑ Schmidt M, et al. (2002) In budding yeast, contraction of the actomyosin ring and formation of the primary septum at cytokinesis depend on each other. J Cell Sci 115(Pt 2):293-302 SGD PMID 11839781
- ↑ Teh EM, et al. (2009) Retention of Chs2p in the ER requires N-terminal CDK1-phosphorylation sites. Cell Cycle 8(18):2964-74 SGD PMID 19713768
- ↑ Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
- ↑ submitted by Jeff Ubersax on 2004-01-21
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