Difference between revisions of "YKL166C"
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| + | === Interactions === | ||
| + | [[Category:Topic:Interactions]] | ||
| + | ==== Genetic ==== | ||
| + | [[Category:Topic:Interactions:Genetic]] | ||
| + | '''Strain Background''': S288C, W303, industrial<br> | ||
| + | Genetic interaction with ATF1 [[Category:Genetic Interactions with ATF1]]<br>'''Mutation type(s)''': deletion/partial inactivating | ||
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| + | ATF1 is transcriptionally induced by glucose and sucrose. This regulation depends on Ras/cAMP/PKA signaling. Long-term expression of ATF1 requires both a fermentable carbon source and a nitrogen source. This regulation depends on FGM signaling. <ref name='S000075255'>Verstrepen KJ, et al. (2003) The Saccharomyces cerevisiae alcohol acetyl transferase gene ATF1 is a target of the cAMP/PKA and FGM nutrient-signalling pathways. FEMS Yeast Res 4(3):285-96 {{SGDpaper|S000075255}} PMID 14654433</ref> <ref name = 'CAset9888-2004-03-11'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=9888 Kevin J Verstrepen] on 2004-03-11</ref> | ||
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| + | {{ShortCenteredHR}} | ||
__TOC__ | __TOC__ | ||
==Community Commentary== | ==Community Commentary== | ||
{{CommentaryHelp}} | {{CommentaryHelp}} | ||
| + | === Interactions === | ||
| + | [[Category:Topic:Interactions]] | ||
| + | ==== Genetic ==== | ||
| + | [[Category:Topic:Interactions:Genetic]] | ||
| + | |||
| + | '''Strain Background''': S288C, W303, industrial<br> | ||
| + | Genetic interaction with ATF1 [[Category:Genetic Interactions with ATF1]]<br>'''Mutation type(s)''': deletion/partial inactivating | ||
| + | |||
| + | ATF1 is transcriptionally induced by glucose and sucrose. This regulation depends on Ras/cAMP/PKA signaling. Long-term expression of ATF1 requires both a fermentable carbon source and a nitrogen source. This regulation depends on FGM signaling. <ref name='S000075255'>Verstrepen KJ, et al. (2003) The Saccharomyces cerevisiae alcohol acetyl transferase gene ATF1 is a target of the cAMP/PKA and FGM nutrient-signalling pathways. FEMS Yeast Res 4(3):285-96 {{SGDpaper|S000075255}} PMID 14654433</ref> <ref name = 'CAset9888-2004-03-11'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=9888 Kevin J Verstrepen] on 2004-03-11</ref> | ||
| + | {{ShortCenteredHR}} | ||
==References== | ==References== | ||
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Revision as of 16:05, 23 January 2007
Share your knowledge...Edit this entry!
| Systematic name | YKL166C | |
| Gene name | TPK3 | |
| Aliases | ||
| Feature type | ORF, Verified | |
| Coordinates | Chr XI:135710..134514 | |
| Don't edit this box! It's automatically regenerated, and edits will be lost when the update script runs. | ||
Description of YKL166C: Subunit of cAMP-dependent protein kinase, which contains Tpk1p, Tpk2p, Tpk3p, and regulatory subunit Bcy1p; promotes growth in response to nutrients; mediates induction of apoptosis due to actin-mediated hyperactivation of Ras signaling[1][2][3][4][5]
Interactions
Genetic
Strain Background: S288C, W303, industrial
Genetic interaction with ATF1
Mutation type(s): deletion/partial inactivating
ATF1 is transcriptionally induced by glucose and sucrose. This regulation depends on Ras/cAMP/PKA signaling. Long-term expression of ATF1 requires both a fermentable carbon source and a nitrogen source. This regulation depends on FGM signaling. [6] [7]
Contents
Community Commentary
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Interactions
Genetic
Strain Background: S288C, W303, industrial
Genetic interaction with ATF1
Mutation type(s): deletion/partial inactivating
ATF1 is transcriptionally induced by glucose and sucrose. This regulation depends on Ras/cAMP/PKA signaling. Long-term expression of ATF1 requires both a fermentable carbon source and a nitrogen source. This regulation depends on FGM signaling. [6] [7]
References
See Help:References on how to add references
- ↑ Gourlay CW and Ayscough KR (2006) Actin-induced hyperactivation of the Ras signaling pathway leads to apoptosis in Saccharomyces cerevisiae. Mol Cell Biol 26(17):6487-501 SGD PMID 16914733
- ↑ Pan X and Heitman J (1999) Cyclic AMP-dependent protein kinase regulates pseudohyphal differentiation in Saccharomyces cerevisiae. Mol Cell Biol 19(7):4874-87 SGD PMID 10373537
- ↑ Toda T, et al. (1987) Cloning and characterization of BCY1, a locus encoding a regulatory subunit of the cyclic AMP-dependent protein kinase in Saccharomyces cerevisiae. Mol Cell Biol 7(4):1371-7 SGD PMID 3037314
- ↑ Ordiz I, et al. (1996) Glucose-induced inactivation of isocitrate lyase in Saccharomyces cerevisiae is mediated by the cAMP-dependent protein kinase catalytic subunits Tpk1 and Tpk2. FEBS Lett 385(1-2):43-6 SGD PMID 8641464
- ↑ Toda T, et al. (1987) Three different genes in S. cerevisiae encode the catalytic subunits of the cAMP-dependent protein kinase. Cell 50(2):277-87 SGD PMID 3036373
- ↑ 6.0 6.1 Verstrepen KJ, et al. (2003) The Saccharomyces cerevisiae alcohol acetyl transferase gene ATF1 is a target of the cAMP/PKA and FGM nutrient-signalling pathways. FEMS Yeast Res 4(3):285-96 SGD PMID 14654433
- ↑ 7.0 7.1 submitted by Kevin J Verstrepen on 2004-03-11
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