Difference between revisions of "YKL204W"

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'''Description of YKL204W:''' eIF4E-associated protein, binds eIF4E and inhibits cap-dependent translation, also functions independently of eIF4E to maintain genetic stability; plays a role in cell growth, implicated in the TOR signaling cascade<ref name='S000043142'>Cosentino GP, et al. (2000) Eap1p, a novel eukaryotic translation initiation factor 4E-associated protein in Saccharomyces cerevisiae. Mol Cell Biol 20(13):4604-13 {{SGDpaper|S000043142}} PMID 10848587</ref><ref name='S000059777'>Chial HJ, et al. (2000) Yeast Eap1p, an eIF4E-associated protein, has a separate function involving genetic stability. Curr Biol 10(23):1519-22
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'''Description of YKL204W:''' eIF4E-associated protein, competes with eIF4G for binding to eIF4E; inhibits cap-dependent translation; functions independently of eIF4E to maintain genetic stability; plays a role in cell growth, implicated in the TOR signaling cascade<ref name='S000043142'>Cosentino GP, et al. (2000) Eap1p, a novel eukaryotic translation initiation factor 4E-associated protein in Saccharomyces cerevisiae. Mol Cell Biol 20(13):4604-13 {{SGDpaper|S000043142}} PMID 10848587</ref><ref name='S000059777'>Chial HJ, et al. (2000) Yeast Eap1p, an eIF4E-associated protein, has a separate function involving genetic stability. Curr Biol 10(23):1519-22
 
  {{SGDpaper|S000059777}} PMID 11114520</ref>
 
  {{SGDpaper|S000059777}} PMID 11114520</ref>
 
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Revision as of 14:05, 13 July 2009

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Systematic name YKL204W
Gene name EAP1
Aliases
Feature type ORF, Verified
Coordinates Chr XI:53705..55603
Primary SGDID S000001687


Description of YKL204W: eIF4E-associated protein, competes with eIF4G for binding to eIF4E; inhibits cap-dependent translation; functions independently of eIF4E to maintain genetic stability; plays a role in cell growth, implicated in the TOR signaling cascade[1][2]




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References

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  1. Cosentino GP, et al. (2000) Eap1p, a novel eukaryotic translation initiation factor 4E-associated protein in Saccharomyces cerevisiae. Mol Cell Biol 20(13):4604-13 SGD PMID 10848587
  2. Chial HJ, et al. (2000) Yeast Eap1p, an eIF4E-associated protein, has a separate function involving genetic stability. Curr Biol 10(23):1519-22 SGD PMID 11114520

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