Difference between revisions of "YEL048C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000774 YEL048C]  
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000774 YEL048C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||'' ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''TCA17 ''
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''          ||'' ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''          ||'' ''
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'''Description of YEL048C:''' Protein that exhibits genetic and physical interactions with TRAPP subunits; human ortholog TRAPPC2L associates with human TRAPP complexes and is involved in Golgi dynamics; mutation is synthetically lethal with gcs1 deletion<ref name='S000114387'>Robinson M, et al. (2006) The Gcs1 Arf-GAP mediates Snc1,2 v-SNARE retrieval to the Golgi in yeast. Mol Biol Cell 17(4):1845-58 {{SGDpaper|S000114387}} PMID 16452633</ref><ref name='S000130251'>Scrivens PJ, et al. (2009) TRAPPC2L is a Novel, Highly Conserved TRAPP-Interacting Protein. Traffic
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'''Description of YEL048C:''' Protein that interacts with subunits of the TRAPP complex and may play a role its assembly or stability; mutation is synthetically lethal with gcs1 deletion; Sedlin_N family member; human Sedlin mutations cause the skeletal disorder SEDT<ref name='S000114387'>Robinson M, et al. (2006) The Gcs1 Arf-GAP mediates Snc1,2 v-SNARE retrieval to the Golgi in yeast. Mol Biol Cell 17(4):1845-58 {{SGDpaper|S000114387}} PMID 16452633</ref><ref name='S000130484'>Montpetit B and Conibear E (2009) Identification of the novel TRAPP associated protein Tca17. Traffic {{SGDpaper|S000130484}} PMID 19220810</ref><ref name='S000130251'>Scrivens PJ, et al. (2009) TRAPPC2L is a Novel, Highly Conserved TRAPP-Interacting Protein. Traffic
 
  {{SGDpaper|S000130251}} PMID 19416478</ref>
 
  {{SGDpaper|S000130251}} PMID 19416478</ref>
 
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Revision as of 13:05, 3 June 2009

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Systematic name YEL048C
Gene name TCA17
Aliases
Feature type ORF, Verified
Coordinates Chr V:65167..64709
Primary SGDID S000000774


Description of YEL048C: Protein that interacts with subunits of the TRAPP complex and may play a role its assembly or stability; mutation is synthetically lethal with gcs1 deletion; Sedlin_N family member; human Sedlin mutations cause the skeletal disorder SEDT[1][2][3]




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References

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  1. Robinson M, et al. (2006) The Gcs1 Arf-GAP mediates Snc1,2 v-SNARE retrieval to the Golgi in yeast. Mol Biol Cell 17(4):1845-58 SGD PMID 16452633
  2. Montpetit B and Conibear E (2009) Identification of the novel TRAPP associated protein Tca17. Traffic SGD PMID 19220810
  3. Scrivens PJ, et al. (2009) TRAPPC2L is a Novel, Highly Conserved TRAPP-Interacting Protein. Traffic SGD PMID 19416478

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