Difference between revisions of "YOR098C"

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'''Description of YOR098C:''' Nuclear pore complex (NPC) subunit, involved in protein import/export and in export of RNAs, possible karyopherin release factor that accelerates release of karyopherin-cargo complexes after transport across NPC; potential Cdc28p substrate<ref name='S000069856'>Gilchrist D, et al. (2002) Accelerating the rate of disassembly of karyopherin.cargo complexes. J Biol Chem 277(20):18161-72 {{SGDpaper|S000069856}} PMID 11867631</ref><ref name='S000051060'>Davis LI and Fink GR (1990) The NUP1 gene encodes an essential component of the yeast nuclear pore complex. Cell 61(6):965-78 {{SGDpaper|S000051060}} PMID 2190694</ref><ref name='S000040743'>Bogerd AM, et al. (1994) nup1 mutants exhibit pleiotropic defects in nuclear pore complex function. J Cell Biol 127(2):319-32
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'''Description of YOR098C:''' Nuclear pore complex (NPC) subunit, involved in protein import/export and in export of RNAs, possible karyopherin release factor that accelerates release of karyopherin-cargo complexes after transport across NPC; potential Cdc28p substrate<ref name='S000040743'>Bogerd AM, et al. (1994) nup1 mutants exhibit pleiotropic defects in nuclear pore complex function. J Cell Biol 127(2):319-32 {{SGDpaper|S000040743}} PMID 7929578</ref><ref name='S000051060'>Davis LI and Fink GR (1990) The NUP1 gene encodes an essential component of the yeast nuclear pore complex. Cell 61(6):965-78 {{SGDpaper|S000051060}} PMID 2190694</ref><ref name='S000069856'>Gilchrist D, et al. (2002) Accelerating the rate of disassembly of karyopherin.cargo complexes. J Biol Chem 277(20):18161-72
  {{SGDpaper|S000040743}} PMID 7929578</ref>
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  {{SGDpaper|S000069856}} PMID 11867631</ref>
 
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Revision as of 13:05, 31 March 2009

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Systematic name YOR098C
Gene name NUP1
Aliases
Feature type ORF, Verified
Coordinates Chr XV:511179..507949
Primary SGDID S000005624


Description of YOR098C: Nuclear pore complex (NPC) subunit, involved in protein import/export and in export of RNAs, possible karyopherin release factor that accelerates release of karyopherin-cargo complexes after transport across NPC; potential Cdc28p substrate[1][2][3]




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Protein Details

Protein Modification

Modification(s): Phosphorylation

Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [4] [5]





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References

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  1. Bogerd AM, et al. (1994) nup1 mutants exhibit pleiotropic defects in nuclear pore complex function. J Cell Biol 127(2):319-32 SGD PMID 7929578
  2. Davis LI and Fink GR (1990) The NUP1 gene encodes an essential component of the yeast nuclear pore complex. Cell 61(6):965-78 SGD PMID 2190694
  3. Gilchrist D, et al. (2002) Accelerating the rate of disassembly of karyopherin.cargo complexes. J Biol Chem 277(20):18161-72 SGD PMID 11867631
  4. Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
  5. submitted by Jeff Ubersax on 2004-01-29

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