Difference between revisions of "YOL112W"
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| − | '''Description of YOL112W:''' GTPase-activating protein of the Ras superfamily that acts primarily on Sec4p, localizes to the bud site and bud tip, has similarity to Msb3p; msb3 msb4 double mutation causes defects in secretion and actin organization<ref name=' | + | '''Description of YOL112W:''' GTPase-activating protein of the Ras superfamily that acts primarily on Sec4p, localizes to the bud site and bud tip, has similarity to Msb3p; msb3 msb4 double mutation causes defects in secretion and actin organization<ref name='S000040830'>Bi E, et al. (2000) Identification of novel, evolutionarily conserved Cdc42p-interacting proteins and of redundant pathways linking Cdc24p and Cdc42p to actin polarization in yeast. Mol Biol Cell 11(2):773-93 {{SGDpaper|S000040830}} PMID 10679030</ref><ref name='S000062162'>Albert S and Gallwitz D (2000) Msb4p, a protein involved in Cdc42p-dependent organization of the actin cytoskeleton, is a Ypt/Rab-specific GAP. Biol Chem 381(5-6):453-6 {{SGDpaper|S000062162}} PMID 10937877</ref><ref name='S000073833'>Gao XD, et al. (2003) The GAP activity of Msb3p and Msb4p for the Rab GTPase Sec4p is required for efficient exocytosis and actin organization. J Cell Biol 162(4):635-46 |
| − | {{SGDpaper| | + | {{SGDpaper|S000073833}} PMID 12913108</ref> |
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Revision as of 13:05, 31 March 2009
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| Systematic name | YOL112W |
| Gene name | MSB4 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:106710..108188 |
| Primary SGDID | S000005472 |
Description of YOL112W: GTPase-activating protein of the Ras superfamily that acts primarily on Sec4p, localizes to the bud site and bud tip, has similarity to Msb3p; msb3 msb4 double mutation causes defects in secretion and actin organization[1][2][3]
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References
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- ↑ Bi E, et al. (2000) Identification of novel, evolutionarily conserved Cdc42p-interacting proteins and of redundant pathways linking Cdc24p and Cdc42p to actin polarization in yeast. Mol Biol Cell 11(2):773-93 SGD PMID 10679030
- ↑ Albert S and Gallwitz D (2000) Msb4p, a protein involved in Cdc42p-dependent organization of the actin cytoskeleton, is a Ypt/Rab-specific GAP. Biol Chem 381(5-6):453-6 SGD PMID 10937877
- ↑ Gao XD, et al. (2003) The GAP activity of Msb3p and Msb4p for the Rab GTPase Sec4p is required for efficient exocytosis and actin organization. J Cell Biol 162(4):635-46 SGD PMID 12913108
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