Difference between revisions of "YOL110W"

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'''Description of YOL110W:''' Subunit of a palmitoyltransferase, composed of Shr5p and Erf2p, that adds a palmitoyl lipid moiety to heterolipidated substrates such as Ras1p and Ras2p through a thioester linkage; palmitoylation is required for Ras2p membrane localization<ref name='S000116650'>Roth AF, et al. (2006) Global analysis of protein palmitoylation in yeast. Cell 125(5):1003-13 {{SGDpaper|S000116650}} PMID 16751107</ref><ref name='S000074072'>Dong X, et al. (2003) Palmitoylation and plasma membrane localization of Ras2p by a nonclassical trafficking pathway in Saccharomyces cerevisiae. Mol Cell Biol 23(18):6574-84 {{SGDpaper|S000074072}} PMID 12944483</ref><ref name='S000072560'>Zhao L, et al. (2002) Erf4p and Erf2p form an endoplasmic reticulum-associated complex involved in the plasma membrane localization of yeast Ras proteins. J Biol Chem 277(51):49352-9
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'''Description of YOL110W:''' Subunit of a palmitoyltransferase, composed of Shr5p and Erf2p, that adds a palmitoyl lipid moiety to heterolipidated substrates such as Ras1p and Ras2p through a thioester linkage; palmitoylation is required for Ras2p membrane localization<ref name='S000072560'>Zhao L, et al. (2002) Erf4p and Erf2p form an endoplasmic reticulum-associated complex involved in the plasma membrane localization of yeast Ras proteins. J Biol Chem 277(51):49352-9 {{SGDpaper|S000072560}} PMID 12379641</ref><ref name='S000074072'>Dong X, et al. (2003) Palmitoylation and plasma membrane localization of Ras2p by a nonclassical trafficking pathway in Saccharomyces cerevisiae. Mol Cell Biol 23(18):6574-84 {{SGDpaper|S000074072}} PMID 12944483</ref><ref name='S000116650'>Roth AF, et al. (2006) Global analysis of protein palmitoylation in yeast. Cell 125(5):1003-13
  {{SGDpaper|S000072560}} PMID 12379641</ref>
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  {{SGDpaper|S000116650}} PMID 16751107</ref>
 
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Revision as of 14:05, 31 March 2009

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Systematic name YOL110W
Gene name SHR5
Aliases ERF4
Feature type ORF, Verified
Coordinates Chr XV:109176..109889
Primary SGDID S000005470


Description of YOL110W: Subunit of a palmitoyltransferase, composed of Shr5p and Erf2p, that adds a palmitoyl lipid moiety to heterolipidated substrates such as Ras1p and Ras2p through a thioester linkage; palmitoylation is required for Ras2p membrane localization[1][2][3]




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References

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  1. Zhao L, et al. (2002) Erf4p and Erf2p form an endoplasmic reticulum-associated complex involved in the plasma membrane localization of yeast Ras proteins. J Biol Chem 277(51):49352-9 SGD PMID 12379641
  2. Dong X, et al. (2003) Palmitoylation and plasma membrane localization of Ras2p by a nonclassical trafficking pathway in Saccharomyces cerevisiae. Mol Cell Biol 23(18):6574-84 SGD PMID 12944483
  3. Roth AF, et al. (2006) Global analysis of protein palmitoylation in yeast. Cell 125(5):1003-13 SGD PMID 16751107

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