Difference between revisions of "YNL251C"

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'''Description of YNL251C:''' RNA-binding protein that interacts with the C-terminal domain of the RNA polymerase II large subunit (Rpo21p), preferentially at phosphorylated Ser5; required for transcription termination and 3' end maturation of nonpolyadenylated RNAs<ref name='S000127231'>Vasiljeva L, et al. (2008) The Nrd1-Nab3-Sen1 termination complex interacts with the Ser5-phosphorylated RNA polymerase II C-terminal domain. Nat Struct Mol Biol 15(8):795-804 {{SGDpaper|S000127231}} PMID 18660819</ref><ref name='S000052606'>Steinmetz EJ and Brow DA (1998) Control of pre-mRNA accumulation by the essential yeast protein Nrd1 requires high-affinity transcript binding and a domain implicated in RNA polymerase II association. Proc Natl Acad Sci U S A 95(12):6699-704 {{SGDpaper|S000052606}} PMID 9618475</ref><ref name='S000045868'>Conrad NK, et al. (2000) A yeast heterogeneous nuclear ribonucleoprotein complex associated with RNA polymerase II. Genetics 154(2):557-71
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'''Description of YNL251C:''' RNA-binding protein that interacts with the C-terminal domain of the RNA polymerase II large subunit (Rpo21p), preferentially at phosphorylated Ser5; required for transcription termination and 3' end maturation of nonpolyadenylated RNAs<ref name='S000045868'>Conrad NK, et al. (2000) A yeast heterogeneous nuclear ribonucleoprotein complex associated with RNA polymerase II. Genetics 154(2):557-71 {{SGDpaper|S000045868}} PMID 10655211</ref><ref name='S000052606'>Steinmetz EJ and Brow DA (1998) Control of pre-mRNA accumulation by the essential yeast protein Nrd1 requires high-affinity transcript binding and a domain implicated in RNA polymerase II association. Proc Natl Acad Sci U S A 95(12):6699-704 {{SGDpaper|S000052606}} PMID 9618475</ref><ref name='S000127231'>Vasiljeva L, et al. (2008) The Nrd1-Nab3-Sen1 termination complex interacts with the Ser5-phosphorylated RNA polymerase II C-terminal domain. Nat Struct Mol Biol 15(8):795-804
  {{SGDpaper|S000045868}} PMID 10655211</ref>
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  {{SGDpaper|S000127231}} PMID 18660819</ref>
 
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Revision as of 14:05, 31 March 2009

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Systematic name YNL251C
Gene name NRD1
Aliases
Feature type ORF, Verified
Coordinates Chr XIV:174316..172589
Primary SGDID S000005195


Description of YNL251C: RNA-binding protein that interacts with the C-terminal domain of the RNA polymerase II large subunit (Rpo21p), preferentially at phosphorylated Ser5; required for transcription termination and 3' end maturation of nonpolyadenylated RNAs[1][2][3]




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References

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  1. Conrad NK, et al. (2000) A yeast heterogeneous nuclear ribonucleoprotein complex associated with RNA polymerase II. Genetics 154(2):557-71 SGD PMID 10655211
  2. Steinmetz EJ and Brow DA (1998) Control of pre-mRNA accumulation by the essential yeast protein Nrd1 requires high-affinity transcript binding and a domain implicated in RNA polymerase II association. Proc Natl Acad Sci U S A 95(12):6699-704 SGD PMID 9618475
  3. Vasiljeva L, et al. (2008) The Nrd1-Nab3-Sen1 termination complex interacts with the Ser5-phosphorylated RNA polymerase II C-terminal domain. Nat Struct Mol Biol 15(8):795-804 SGD PMID 18660819

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