Difference between revisions of "YNL138W"
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− | '''Description of YNL138W:''' CAP (cyclase-associated protein) subunit of adenylyl cyclase complex; N-terminus binds adenylyl cyclase and facilitates activation by RAS; C-terminus binds ADP-actin monomers, facilitating regulation of actin dynamics and cell morphogenesis<ref name=' | + | '''Description of YNL138W:''' CAP (cyclase-associated protein) subunit of adenylyl cyclase complex; N-terminus binds adenylyl cyclase and facilitates activation by RAS; C-terminus binds ADP-actin monomers, facilitating regulation of actin dynamics and cell morphogenesis<ref name='S000044067'>Freeman NL, et al. (1995) An actin monomer binding activity localizes to the carboxyl-terminal half of the Saccharomyces cerevisiae cyclase-associated protein. J Biol Chem 270(10):5680-5 {{SGDpaper|S000044067}} PMID 7890691</ref><ref name='S000052385'>Fedor-Chaiken M, et al. (1990) SRV2, a gene required for RAS activation of adenylate cyclase in yeast. Cell 61(2):329-40 {{SGDpaper|S000052385}} PMID 2158860</ref><ref name='S000077571'>Mattila PK, et al. (2004) A high-affinity interaction with ADP-actin monomers underlies the mechanism and in vivo function of Srv2/cyclase-associated protein. Mol Biol Cell 15(11):5158-71 |
− | {{SGDpaper| | + | {{SGDpaper|S000077571}} PMID 15356265</ref> |
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Revision as of 14:05, 31 March 2009
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Systematic name | YNL138W |
Gene name | SRV2 |
Aliases | CAP |
Feature type | ORF, Verified |
Coordinates | Chr XIV:366743..368323 |
Primary SGDID | S000005082 |
Description of YNL138W: CAP (cyclase-associated protein) subunit of adenylyl cyclase complex; N-terminus binds adenylyl cyclase and facilitates activation by RAS; C-terminus binds ADP-actin monomers, facilitating regulation of actin dynamics and cell morphogenesis[1][2][3]
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References
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- ↑ Freeman NL, et al. (1995) An actin monomer binding activity localizes to the carboxyl-terminal half of the Saccharomyces cerevisiae cyclase-associated protein. J Biol Chem 270(10):5680-5 SGD PMID 7890691
- ↑ Fedor-Chaiken M, et al. (1990) SRV2, a gene required for RAS activation of adenylate cyclase in yeast. Cell 61(2):329-40 SGD PMID 2158860
- ↑ Mattila PK, et al. (2004) A high-affinity interaction with ADP-actin monomers underlies the mechanism and in vivo function of Srv2/cyclase-associated protein. Mol Biol Cell 15(11):5158-71 SGD PMID 15356265
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