Difference between revisions of "YNL053W"
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| − | '''Description of YNL053W:''' Dual-specificity protein phosphatase; exists in 2 isoforms; required for maintenance of a low level of signaling through the cell integrity pathway, adaptive response to pheromone; regulates and is regulated by Slt2p; dephosphorylates Fus3p<ref name=' | + | '''Description of YNL053W:''' Dual-specificity protein phosphatase; exists in 2 isoforms; required for maintenance of a low level of signaling through the cell integrity pathway, adaptive response to pheromone; regulates and is regulated by Slt2p; dephosphorylates Fus3p<ref name='S000041317'>Doi K, et al. (1994) MSG5, a novel protein phosphatase promotes adaptation to pheromone response in S. cerevisiae. EMBO J 13(1):61-70 {{SGDpaper|S000041317}} PMID 8306972</ref><ref name='S000075679'>Flandez M, et al. (2004) Reciprocal regulation between Slt2 MAPK and isoforms of Msg5 dual-specificity protein phosphatase modulates the yeast cell integrity pathway. J Biol Chem 279(12):11027-34 {{SGDpaper|S000075679}} PMID 14703512</ref><ref name='S000124602'>Blackwell E, et al. (2007) The pheromone-induced nuclear accumulation of the Fus3 MAPK in yeast depends on its phosphorylation state and on Dig1 and Dig2. BMC Cell Biol 8:44 |
| − | {{SGDpaper| | + | {{SGDpaper|S000124602}} PMID 17963515</ref> |
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Revision as of 13:05, 31 March 2009
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| Systematic name | YNL053W |
| Gene name | MSG5 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XIV:529943..531412 |
| Primary SGDID | S000004998 |
Description of YNL053W: Dual-specificity protein phosphatase; exists in 2 isoforms; required for maintenance of a low level of signaling through the cell integrity pathway, adaptive response to pheromone; regulates and is regulated by Slt2p; dephosphorylates Fus3p[1][2][3]
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References
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- ↑ Doi K, et al. (1994) MSG5, a novel protein phosphatase promotes adaptation to pheromone response in S. cerevisiae. EMBO J 13(1):61-70 SGD PMID 8306972
- ↑ Flandez M, et al. (2004) Reciprocal regulation between Slt2 MAPK and isoforms of Msg5 dual-specificity protein phosphatase modulates the yeast cell integrity pathway. J Biol Chem 279(12):11027-34 SGD PMID 14703512
- ↑ Blackwell E, et al. (2007) The pheromone-induced nuclear accumulation of the Fus3 MAPK in yeast depends on its phosphorylation state and on Dig1 and Dig2. BMC Cell Biol 8:44 SGD PMID 17963515
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