Difference between revisions of "YMR260C"
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| − | '''Description of YMR260C:''' Translation initiation factor eIF1A, essential protein that forms a complex with Sui1p (eIF1) and the 40S ribosomal subunit and scans for the start codon; C-terminus associates with Fun12p (eIF5B); N terminus interacts with eIF2 and eIF3<ref name='S000081107'>Maag D, et al. (2005) A conformational change in the eukaryotic translation preinitiation complex and release of eIF1 signal recognition of the start codon. Mol Cell 17(2):265-75 {{SGDpaper|S000081107}} PMID 15664195</ref><ref name='S000072611'>Olsen DS, et al. (2003) Domains of eIF1A that mediate binding to eIF2, eIF3 and eIF5B and promote ternary complex recruitment in vivo. EMBO J 22(2):193-204 {{SGDpaper|S000072611}} PMID 12514125 | + | '''Description of YMR260C:''' Translation initiation factor eIF1A, essential protein that forms a complex with Sui1p (eIF1) and the 40S ribosomal subunit and scans for the start codon; C-terminus associates with Fun12p (eIF5B); N terminus interacts with eIF2 and eIF3<ref name='S000045276'>Wei CL, et al. (1995) Characterization of yeast translation initiation factor 1A and cloning of its essential gene. J Biol Chem 270(39):22788-94 {{SGDpaper|S000045276}} PMID 7559407</ref><ref name='S000081107'>Maag D, et al. (2005) A conformational change in the eukaryotic translation preinitiation complex and release of eIF1 signal recognition of the start codon. Mol Cell 17(2):265-75 {{SGDpaper|S000081107}} PMID 15664195</ref><ref name='S000072611'>Olsen DS, et al. (2003) Domains of eIF1A that mediate binding to eIF2, eIF3 and eIF5B and promote ternary complex recruitment in vivo. EMBO J 22(2):193-204 |
| − | + | {{SGDpaper|S000072611}} PMID 12514125</ref> | |
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Revision as of 14:05, 31 March 2009
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| Systematic name | YMR260C |
| Gene name | TIF11 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XIII:789838..789377 |
| Primary SGDID | S000004873 |
Description of YMR260C: Translation initiation factor eIF1A, essential protein that forms a complex with Sui1p (eIF1) and the 40S ribosomal subunit and scans for the start codon; C-terminus associates with Fun12p (eIF5B); N terminus interacts with eIF2 and eIF3[1][2][3]
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References
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- ↑ Wei CL, et al. (1995) Characterization of yeast translation initiation factor 1A and cloning of its essential gene. J Biol Chem 270(39):22788-94 SGD PMID 7559407
- ↑ Maag D, et al. (2005) A conformational change in the eukaryotic translation preinitiation complex and release of eIF1 signal recognition of the start codon. Mol Cell 17(2):265-75 SGD PMID 15664195
- ↑ Olsen DS, et al. (2003) Domains of eIF1A that mediate binding to eIF2, eIF3 and eIF5B and promote ternary complex recruitment in vivo. EMBO J 22(2):193-204 SGD PMID 12514125
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