Difference between revisions of "YMR115W"
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| − | '''Description of YMR115W:''' Subunit of the mitochondrial (mt) i-AAA protease supercomplex, which degrades misfolded mitochondrial proteins; forms a subcomplex with Mgr1p that binds to substrates to facilitate proteolysis; required for growth of cells lacking mtDNA<ref name=' | + | '''Description of YMR115W:''' Subunit of the mitochondrial (mt) i-AAA protease supercomplex, which degrades misfolded mitochondrial proteins; forms a subcomplex with Mgr1p that binds to substrates to facilitate proteolysis; required for growth of cells lacking mtDNA<ref name='S000117178'>Reinders J, et al. (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J Proteome Res 5(7):1543-54 {{SGDpaper|S000117178}} PMID 16823961</ref><ref name='S000127993'>Dunn CD, et al. (2008) Mgr3p and Mgr1p are adaptors for the mitochondrial i-AAA protease complex. Mol Biol Cell 19(12):5387-97 |
| − | {{SGDpaper| | + | {{SGDpaper|S000127993}} PMID 18843051</ref> |
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Revision as of 14:05, 31 March 2009
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| Systematic name | YMR115W |
| Gene name | MGR3 |
| Aliases | FMP24 |
| Feature type | ORF, Verified |
| Coordinates | Chr XIII:497703..499208 |
| Primary SGDID | S000004721 |
Description of YMR115W: Subunit of the mitochondrial (mt) i-AAA protease supercomplex, which degrades misfolded mitochondrial proteins; forms a subcomplex with Mgr1p that binds to substrates to facilitate proteolysis; required for growth of cells lacking mtDNA[1][2]
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References
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- ↑ Reinders J, et al. (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J Proteome Res 5(7):1543-54 SGD PMID 16823961
- ↑ Dunn CD, et al. (2008) Mgr3p and Mgr1p are adaptors for the mitochondrial i-AAA protease complex. Mol Biol Cell 19(12):5387-97 SGD PMID 18843051
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