Difference between revisions of "YLR369W"
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| − | '''Description of YLR369W:''' Mitochondrial hsp70-type molecular chaperone, required for assembly of iron/sulfur clusters into proteins at a step after cluster synthesis, and for maturation of Yfh1p, which is a homolog of human frataxin implicated in Friedreich's ataxia<ref name=' | + | '''Description of YLR369W:''' Mitochondrial hsp70-type molecular chaperone, required for assembly of iron/sulfur clusters into proteins at a step after cluster synthesis, and for maturation of Yfh1p, which is a homolog of human frataxin implicated in Friedreich's ataxia<ref name='S000040492'>Knight SA, et al. (1998) Mt-Hsp70 homolog, Ssc2p, required for maturation of yeast frataxin and mitochondrial iron homeostasis. J Biol Chem 273(29):18389-93 {{SGDpaper|S000040492}} PMID 9660806</ref><ref name='S000068798'>Muhlenhoff U, et al. (2003) Components involved in assembly and dislocation of iron-sulfur clusters on the scaffold protein Isu1p. EMBO J 22(18):4815-25 |
| − | {{SGDpaper| | + | {{SGDpaper|S000068798}} PMID 12970193</ref> |
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Revision as of 13:05, 31 March 2009
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| Systematic name | YLR369W |
| Gene name | SSQ1 |
| Aliases | SSC2, SSH1 |
| Feature type | ORF, Verified |
| Coordinates | Chr XII:859551..861524 |
| Primary SGDID | S000004361 |
Description of YLR369W: Mitochondrial hsp70-type molecular chaperone, required for assembly of iron/sulfur clusters into proteins at a step after cluster synthesis, and for maturation of Yfh1p, which is a homolog of human frataxin implicated in Friedreich's ataxia[1][2]
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References
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- ↑ Knight SA, et al. (1998) Mt-Hsp70 homolog, Ssc2p, required for maturation of yeast frataxin and mitochondrial iron homeostasis. J Biol Chem 273(29):18389-93 SGD PMID 9660806
- ↑ Muhlenhoff U, et al. (2003) Components involved in assembly and dislocation of iron-sulfur clusters on the scaffold protein Isu1p. EMBO J 22(18):4815-25 SGD PMID 12970193
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