Difference between revisions of "YJL013C"

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'''Description of YJL013C:''' Subunit of the spindle-assembly checkpoint complex, which delays anaphase onset in cells with defects in mitotic spindle assembly; pseudosubstrate inhibitor of APC(Cdc20), the anaphase promoting complex involved in securin (Pds1p) turnover<ref name='S000121952'>Burton JL and Solomon MJ (2007) Mad3p, a pseudosubstrate inhibitor of APCCdc20 in the spindle assembly checkpoint. Genes Dev 21(6):655-67 {{SGDpaper|S000121952}} PMID 17369399</ref><ref name='S000056419'>Hardwick KG, et al. (2000) MAD3 encodes a novel component of the spindle checkpoint which interacts with Bub3p, Cdc20p, and Mad2p. J Cell Biol 148(5):871-82
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'''Description of YJL013C:''' Subunit of the spindle-assembly checkpoint complex, which delays anaphase onset in cells with defects in mitotic spindle assembly; pseudosubstrate inhibitor of APC(Cdc20), the anaphase promoting complex involved in securin (Pds1p) turnover<ref name='S000056419'>Hardwick KG, et al. (2000) MAD3 encodes a novel component of the spindle checkpoint which interacts with Bub3p, Cdc20p, and Mad2p. J Cell Biol 148(5):871-82 {{SGDpaper|S000056419}} PMID 10704439</ref><ref name='S000121952'>Burton JL and Solomon MJ (2007) Mad3p, a pseudosubstrate inhibitor of APCCdc20 in the spindle assembly checkpoint. Genes Dev 21(6):655-67
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  {{SGDpaper|S000121952}} PMID 17369399</ref>
 
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Revision as of 13:05, 31 March 2009

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Systematic name YJL013C
Gene name MAD3
Aliases
Feature type ORF, Verified
Coordinates Chr X:411033..409486
Primary SGDID S000003550


Description of YJL013C: Subunit of the spindle-assembly checkpoint complex, which delays anaphase onset in cells with defects in mitotic spindle assembly; pseudosubstrate inhibitor of APC(Cdc20), the anaphase promoting complex involved in securin (Pds1p) turnover[1][2]




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References

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  1. Hardwick KG, et al. (2000) MAD3 encodes a novel component of the spindle checkpoint which interacts with Bub3p, Cdc20p, and Mad2p. J Cell Biol 148(5):871-82 SGD PMID 10704439
  2. Burton JL and Solomon MJ (2007) Mad3p, a pseudosubstrate inhibitor of APCCdc20 in the spindle assembly checkpoint. Genes Dev 21(6):655-67 SGD PMID 17369399

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