Difference between revisions of "YGR144W"
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| − | '''Description of YGR144W:''' Thiazole synthase, catalyzes formation of a thiazole intermediate during thiamine biosynthesis; required for mitochondrial genome stability in response to DNA damaging agents<ref name=' | + | '''Description of YGR144W:''' Thiazole synthase, catalyzes formation of a thiazole intermediate during thiamine biosynthesis; required for mitochondrial genome stability in response to DNA damaging agents<ref name='S000052703'>Machado CR, et al. (1997) Dual role for the yeast THI4 gene in thiamine biosynthesis and DNA damage tolerance. J Mol Biol 273(1):114-21 {{SGDpaper|S000052703}} PMID 9367751</ref><ref name='S000052526'>Praekelt UM, et al. (1994) Regulation of THI4 (MOL1), a thiamine-biosynthetic gene of Saccharomyces cerevisiae. Yeast 10(4):481-90 {{SGDpaper|S000052526}} PMID 7941734</ref><ref name='S000120887'>Chatterjee A, et al. (2007) Biosynthesis of thiamin thiazole in eukaryotes: conversion of NAD to an advanced intermediate. J Am Chem Soc 129(10):2914-22 {{SGDpaper|S000120887}} PMID 17309261</ref><ref name='S000127167'>Chatterjee A, et al. (2008) Biosynthesis of the thiamin-thiazole in eukaryotes: identification of a thiazole tautomer intermediate. J Am Chem Soc 130(34):11394-8 |
| − | {{SGDpaper| | + | {{SGDpaper|S000127167}} PMID 18652458</ref> |
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Revision as of 13:05, 31 March 2009
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| Systematic name | YGR144W |
| Gene name | THI4 |
| Aliases | ESP35, MOL1 |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:780404..781384 |
| Primary SGDID | S000003376 |
Description of YGR144W: Thiazole synthase, catalyzes formation of a thiazole intermediate during thiamine biosynthesis; required for mitochondrial genome stability in response to DNA damaging agents[1][2][3][4]
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References
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- ↑ Machado CR, et al. (1997) Dual role for the yeast THI4 gene in thiamine biosynthesis and DNA damage tolerance. J Mol Biol 273(1):114-21 SGD PMID 9367751
- ↑ Praekelt UM, et al. (1994) Regulation of THI4 (MOL1), a thiamine-biosynthetic gene of Saccharomyces cerevisiae. Yeast 10(4):481-90 SGD PMID 7941734
- ↑ Chatterjee A, et al. (2007) Biosynthesis of thiamin thiazole in eukaryotes: conversion of NAD to an advanced intermediate. J Am Chem Soc 129(10):2914-22 SGD PMID 17309261
- ↑ Chatterjee A, et al. (2008) Biosynthesis of the thiamin-thiazole in eukaryotes: identification of a thiazole tautomer intermediate. J Am Chem Soc 130(34):11394-8 SGD PMID 18652458
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