Difference between revisions of "YGL179C"
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| − | '''Description of YGL179C:''' Protein kinase, related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome<ref name='S000086812'>Elbing K, et al. (2006) Purification and characterization of the three Snf1-activating kinases of Saccharomyces cerevisiae. Biochem J 393(Pt 3):797-805 {{SGDpaper|S000086812}} PMID 16201971</ref><ref name='S000077210'>Hedbacker K, et al. (2004) Pak1 protein kinase regulates activation and nuclear localization of Snf1-Gal83 protein kinase. Mol Cell Biol 24(18):8255-63 {{SGDpaper|S000077210}} PMID 15340085 | + | '''Description of YGL179C:''' Protein kinase, related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome<ref name='S000086812'>Elbing K, et al. (2006) Purification and characterization of the three Snf1-activating kinases of Saccharomyces cerevisiae. Biochem J 393(Pt 3):797-805 {{SGDpaper|S000086812}} PMID 16201971</ref><ref name='S000077210'>Hedbacker K, et al. (2004) Pak1 protein kinase regulates activation and nuclear localization of Snf1-Gal83 protein kinase. Mol Cell Biol 24(18):8255-63 {{SGDpaper|S000077210}} PMID 15340085</ref><ref name='S000073782'>Sutherland CM, et al. (2003) Elm1p is one of three upstream kinases for the Saccharomyces cerevisiae SNF1 complex. Curr Biol 13(15):1299-305 {{SGDpaper|S000073782}} PMID 12906789</ref><ref name='S000073540'>Nath N, et al. (2003) Yeast Pak1 kinase associates with and activates Snf1. Mol Cell Biol 23(11):3909-17 {{SGDpaper|S000073540}} PMID 12748292</ref><ref name='S000073902'>Hong SP, et al. (2003) Activation of yeast Snf1 and mammalian AMP-activated protein kinase by upstream kinases. Proc Natl Acad Sci U S A 100(15):8839-43 |
| − | {{SGDpaper| | + | {{SGDpaper|S000073902}} PMID 12847291</ref> |
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Revision as of 13:05, 31 March 2009
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| Systematic name | YGL179C |
| Gene name | TOS3 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:165097..163415 |
| Primary SGDID | S000003147 |
Description of YGL179C: Protein kinase, related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome[1][2][3][4][5]
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References
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- ↑ Elbing K, et al. (2006) Purification and characterization of the three Snf1-activating kinases of Saccharomyces cerevisiae. Biochem J 393(Pt 3):797-805 SGD PMID 16201971
- ↑ Hedbacker K, et al. (2004) Pak1 protein kinase regulates activation and nuclear localization of Snf1-Gal83 protein kinase. Mol Cell Biol 24(18):8255-63 SGD PMID 15340085
- ↑ Sutherland CM, et al. (2003) Elm1p is one of three upstream kinases for the Saccharomyces cerevisiae SNF1 complex. Curr Biol 13(15):1299-305 SGD PMID 12906789
- ↑ Nath N, et al. (2003) Yeast Pak1 kinase associates with and activates Snf1. Mol Cell Biol 23(11):3909-17 SGD PMID 12748292
- ↑ Hong SP, et al. (2003) Activation of yeast Snf1 and mammalian AMP-activated protein kinase by upstream kinases. Proc Natl Acad Sci U S A 100(15):8839-43 SGD PMID 12847291
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