Difference between revisions of "YGL136C"

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'''Description of YGL136C:''' Mitochondrial 2' O-ribose methyltransferase, required for methylation of U(2791) in 21S rRNA; MRM2 deletion confers thermosensitive respiration and loss of mitochondrial DNA; has similarity to Spb1p and Trm7p, and to E. coli FtsJ/RrmJ<ref name='S000075306'>Bonnerot C, et al. (2003) Functional redundancy of Spb1p and a snR52-dependent mechanism for the 2'-O-ribose methylation of a conserved rRNA position in yeast. Mol Cell 12(5):1309-15 {{SGDpaper|S000075306}} PMID 14636587</ref><ref name='S000069245'>Pintard L, et al. (2002) MRM2 encodes a novel yeast mitochondrial 21S rRNA methyltransferase. EMBO J 21(5):1139-47
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'''Description of YGL136C:''' Mitochondrial 2' O-ribose methyltransferase, required for methylation of U(2791) in 21S rRNA; MRM2 deletion confers thermosensitive respiration and loss of mitochondrial DNA; has similarity to Spb1p and Trm7p, and to E. coli FtsJ/RrmJ<ref name='S000069245'>Pintard L, et al. (2002) MRM2 encodes a novel yeast mitochondrial 21S rRNA methyltransferase. EMBO J 21(5):1139-47 {{SGDpaper|S000069245}} PMID 11867542</ref><ref name='S000075306'>Bonnerot C, et al. (2003) Functional redundancy of Spb1p and a snR52-dependent mechanism for the 2'-O-ribose methylation of a conserved rRNA position in yeast. Mol Cell 12(5):1309-15
{{SGDpaper|S000069245}} PMID 11867542</ref>
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{{SGDpaper|S000075306}} PMID 14636587</ref>
 
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Revision as of 13:05, 31 March 2009

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Systematic name YGL136C
Gene name MRM2
Aliases
Feature type ORF, Verified
Coordinates Chr VII:253864..252902
Primary SGDID S000003104


Description of YGL136C: Mitochondrial 2' O-ribose methyltransferase, required for methylation of U(2791) in 21S rRNA; MRM2 deletion confers thermosensitive respiration and loss of mitochondrial DNA; has similarity to Spb1p and Trm7p, and to E. coli FtsJ/RrmJ[1][2]




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References

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  1. Pintard L, et al. (2002) MRM2 encodes a novel yeast mitochondrial 21S rRNA methyltransferase. EMBO J 21(5):1139-47 SGD PMID 11867542
  2. Bonnerot C, et al. (2003) Functional redundancy of Spb1p and a snR52-dependent mechanism for the 2'-O-ribose methylation of a conserved rRNA position in yeast. Mol Cell 12(5):1309-15 SGD PMID 14636587

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