Difference between revisions of "YDR400W"
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| − | '''Description of YDR400W:''' Uridine nucleosidase (uridine-cytidine N-ribohydrolase), cleaves N-glycosidic bonds in nucleosides; involved in the pyrimidine salvage and nicotinamide riboside salvage pathways<ref name=' | + | '''Description of YDR400W:''' Uridine nucleosidase (uridine-cytidine N-ribohydrolase), cleaves N-glycosidic bonds in nucleosides; involved in the pyrimidine salvage and nicotinamide riboside salvage pathways<ref name='S000055858'>Kurtz JE, et al. (1999) New insights into the pyrimidine salvage pathway of Saccharomyces cerevisiae: requirement of six genes for cytidine metabolism. Curr Genet 36(3):130-6 {{SGDpaper|S000055858}} PMID 10501935</ref><ref name='S000069484'>Mitterbauer R, et al. (2002) Saccharomyces cerevisiae URH1 (encoding uridine-cytidine N-ribohydrolase): functional complementation by a nucleoside hydrolase from a protozoan parasite and by a mammalian uridine phosphorylase. Appl Environ Microbiol 68(3):1336-43 {{SGDpaper|S000069484}} PMID 11872485</ref><ref name='S000070131'>Kurtz JE, et al. (2002) The URH1 uridine ribohydrolase of Saccharomyces cerevisiae. Curr Genet 41(3):132-41 {{SGDpaper|S000070131}} PMID 12111094</ref><ref name='S000122625'>Belenky P, et al. (2007) Nicotinamide riboside promotes Sir2 silencing and extends lifespan via Nrk and Urh1/Pnp1/Meu1 pathways to NAD+. Cell 129(3):473-84 |
| − | {{SGDpaper| | + | {{SGDpaper|S000122625}} PMID 17482543</ref> |
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Revision as of 13:05, 31 March 2009
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| Systematic name | YDR400W |
| Gene name | URH1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:1271056..1272078 |
| Primary SGDID | S000002808 |
Description of YDR400W: Uridine nucleosidase (uridine-cytidine N-ribohydrolase), cleaves N-glycosidic bonds in nucleosides; involved in the pyrimidine salvage and nicotinamide riboside salvage pathways[1][2][3][4]
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References
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- ↑ Kurtz JE, et al. (1999) New insights into the pyrimidine salvage pathway of Saccharomyces cerevisiae: requirement of six genes for cytidine metabolism. Curr Genet 36(3):130-6 SGD PMID 10501935
- ↑ Mitterbauer R, et al. (2002) Saccharomyces cerevisiae URH1 (encoding uridine-cytidine N-ribohydrolase): functional complementation by a nucleoside hydrolase from a protozoan parasite and by a mammalian uridine phosphorylase. Appl Environ Microbiol 68(3):1336-43 SGD PMID 11872485
- ↑ Kurtz JE, et al. (2002) The URH1 uridine ribohydrolase of Saccharomyces cerevisiae. Curr Genet 41(3):132-41 SGD PMID 12111094
- ↑ Belenky P, et al. (2007) Nicotinamide riboside promotes Sir2 silencing and extends lifespan via Nrk and Urh1/Pnp1/Meu1 pathways to NAD+. Cell 129(3):473-84 SGD PMID 17482543
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