Difference between revisions of "YDR335W"

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'''Description of YDR335W:''' Karyopherin involved in nuclear import and export; shown to be responsible for nuclear import of replication protein A and for export of several proteins including Swi6p, Far1p, and Pho4p; cargo dissociation involves binding to RanGTP<ref name='S000073233'>Queralt E and Igual JC (2003) Cell cycle activation of the Swi6p transcription factor is linked to nucleocytoplasmic shuttling. Mol Cell Biol 23(9):3126-40 {{SGDpaper|S000073233}} PMID 12697814</ref><ref name='S000059972'>Yoshida K and Blobel G (2001) The karyopherin Kap142p/Msn5p mediates nuclear import and nuclear export of different cargo proteins. J Cell Biol 152(4):729-40 {{SGDpaper|S000059972}} PMID 11266464</ref><ref name='S000055677'>Alepuz PM, et al. (1999) The Saccharomyces cerevisiae RanGTP-binding protein msn5p is involved in different signal transduction pathways. Genetics 153(3):1219-31 {{SGDpaper|S000055677}} PMID 10545454</ref><ref name='S000052885'>Kaffman A, et al. (1998) The receptor Msn5 exports the phosphorylated transcription factor Pho4 out of the nucleus. Nature 396(6710):482-6 {{SGDpaper|S000052885}} PMID 9853758</ref><ref name='S000048425'>Blondel M, et al. (1999) Nuclear export of Far1p in response to pheromones requires the export receptor Msn5p/Ste21p. Genes Dev 13(17):2284-300
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'''Description of YDR335W:''' Karyopherin involved in nuclear import and export; shown to be responsible for nuclear import of replication protein A and for export of several proteins including Swi6p, Far1p, and Pho4p; cargo dissociation involves binding to RanGTP<ref name='S000048425'>Blondel M, et al. (1999) Nuclear export of Far1p in response to pheromones requires the export receptor Msn5p/Ste21p. Genes Dev 13(17):2284-300 {{SGDpaper|S000048425}} PMID 10485850</ref><ref name='S000052885'>Kaffman A, et al. (1998) The receptor Msn5 exports the phosphorylated transcription factor Pho4 out of the nucleus. Nature 396(6710):482-6 {{SGDpaper|S000052885}} PMID 9853758</ref><ref name='S000055677'>Alepuz PM, et al. (1999) The Saccharomyces cerevisiae RanGTP-binding protein msn5p is involved in different signal transduction pathways. Genetics 153(3):1219-31 {{SGDpaper|S000055677}} PMID 10545454</ref><ref name='S000059972'>Yoshida K and Blobel G (2001) The karyopherin Kap142p/Msn5p mediates nuclear import and nuclear export of different cargo proteins. J Cell Biol 152(4):729-40 {{SGDpaper|S000059972}} PMID 11266464</ref><ref name='S000073233'>Queralt E and Igual JC (2003) Cell cycle activation of the Swi6p transcription factor is linked to nucleocytoplasmic shuttling. Mol Cell Biol 23(9):3126-40
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  {{SGDpaper|S000073233}} PMID 12697814</ref>
 
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Revision as of 13:05, 31 March 2009

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Systematic name YDR335W
Gene name MSN5
Aliases KAP142, STE21
Feature type ORF, Verified
Coordinates Chr IV:1141163..1144837
Primary SGDID S000002743


Description of YDR335W: Karyopherin involved in nuclear import and export; shown to be responsible for nuclear import of replication protein A and for export of several proteins including Swi6p, Far1p, and Pho4p; cargo dissociation involves binding to RanGTP[1][2][3][4][5]




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References

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  1. Blondel M, et al. (1999) Nuclear export of Far1p in response to pheromones requires the export receptor Msn5p/Ste21p. Genes Dev 13(17):2284-300 SGD PMID 10485850
  2. Kaffman A, et al. (1998) The receptor Msn5 exports the phosphorylated transcription factor Pho4 out of the nucleus. Nature 396(6710):482-6 SGD PMID 9853758
  3. Alepuz PM, et al. (1999) The Saccharomyces cerevisiae RanGTP-binding protein msn5p is involved in different signal transduction pathways. Genetics 153(3):1219-31 SGD PMID 10545454
  4. Yoshida K and Blobel G (2001) The karyopherin Kap142p/Msn5p mediates nuclear import and nuclear export of different cargo proteins. J Cell Biol 152(4):729-40 SGD PMID 11266464
  5. Queralt E and Igual JC (2003) Cell cycle activation of the Swi6p transcription factor is linked to nucleocytoplasmic shuttling. Mol Cell Biol 23(9):3126-40 SGD PMID 12697814

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