Difference between revisions of "YFL010C"

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'''Description of YFL010C:''' WW domain containing protein of unknown function; binds to Mca1p, a caspase-related protease that regulates H2O2-induced apoptosis; overexpression causes Gi phase growth arrest and clonal death that is suppressed by overexpression of MCA1<ref name='S000082266'>Stevenson LF, et al. (2001) A large-scale overexpression screen in Saccharomyces cerevisiae identifies previously uncharacterized cell cycle genes. Proc Natl Acad Sci U S A 98(7):3946-51 {{SGDpaper|S000082266}} PMID 11274415</ref><ref name='S000070033'>Madeo F, et al. (2002) A caspase-related protease regulates apoptosis in yeast. Mol Cell 9(4):911-7 {{SGDpaper|S000070033}} PMID 11983181</ref><ref name='S000069959'>Szallies A, et al. (2002) A metacaspase of Trypanosoma brucei causes loss of respiration competence and clonal death in the yeast Saccharomyces cerevisiae. FEBS Lett 517(1-3):144-50 {{SGDpaper|S000069959}} PMID 12062425</ref><ref name='S000043128'>Uetz P, et al. (2000) A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae. Nature 403(6770):623-7
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'''Description of YFL010C:''' WW domain containing protein of unknown function; binds to Mca1p, a caspase-related protease that regulates H2O2-induced apoptosis; overexpression causes Gi phase growth arrest and clonal death that is suppressed by overexpression of MCA1<ref name='S000043128'>Uetz P, et al. (2000) A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae. Nature 403(6770):623-7 {{SGDpaper|S000043128}} PMID 10688190</ref><ref name='S000070033'>Madeo F, et al. (2002) A caspase-related protease regulates apoptosis in yeast. Mol Cell 9(4):911-7 {{SGDpaper|S000070033}} PMID 11983181</ref><ref name='S000069959'>Szallies A, et al. (2002) A metacaspase of Trypanosoma brucei causes loss of respiration competence and clonal death in the yeast Saccharomyces cerevisiae. FEBS Lett 517(1-3):144-50 {{SGDpaper|S000069959}} PMID 12062425</ref><ref name='S000082266'>Stevenson LF, et al. (2001) A large-scale overexpression screen in Saccharomyces cerevisiae identifies previously uncharacterized cell cycle genes. Proc Natl Acad Sci U S A 98(7):3946-51
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  {{SGDpaper|S000082266}} PMID 11274415</ref>
 
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Revision as of 14:05, 31 March 2009

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Systematic name YFL010C
Gene name WWM1
Aliases
Feature type ORF, Verified
Coordinates Chr VI:115737..115102
Primary SGDID S000001884


Description of YFL010C: WW domain containing protein of unknown function; binds to Mca1p, a caspase-related protease that regulates H2O2-induced apoptosis; overexpression causes Gi phase growth arrest and clonal death that is suppressed by overexpression of MCA1[1][2][3][4]




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References

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  1. Uetz P, et al. (2000) A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae. Nature 403(6770):623-7 SGD PMID 10688190
  2. Madeo F, et al. (2002) A caspase-related protease regulates apoptosis in yeast. Mol Cell 9(4):911-7 SGD PMID 11983181
  3. Szallies A, et al. (2002) A metacaspase of Trypanosoma brucei causes loss of respiration competence and clonal death in the yeast Saccharomyces cerevisiae. FEBS Lett 517(1-3):144-50 SGD PMID 12062425
  4. Stevenson LF, et al. (2001) A large-scale overexpression screen in Saccharomyces cerevisiae identifies previously uncharacterized cell cycle genes. Proc Natl Acad Sci U S A 98(7):3946-51 SGD PMID 11274415

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