Difference between revisions of "YKR052C"

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'''Description of YKR052C:''' Mitochondrial iron transporter of the mitochondrial carrier family (MCF), very similar to and functionally redundant with Mrs3p; functions under low-iron conditions; may transport other cations in addition to iron<ref name='S000075094'>Muhlenhoff U, et al. (2003) A specific role of the yeast mitochondrial carriers MRS3/4p in mitochondrial iron acquisition under iron-limiting conditions. J Biol Chem 278(42):40612-20
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'''Description of YKR052C:''' Iron transporter that mediates Fe2+ transport across the inner mitochondrial membrane; mitochondrial carrier family member, similar to and functionally redundant with Mrs3p; active under low-iron conditions; may transport other cations<ref name='S000048548'>Wiesenberger G, et al. (1991) MRS3 and MRS4, two suppressors of mtRNA splicing defects in yeast, are new members of the mitochondrial carrier family. J Mol Biol 217(1):23-37 {{SGDpaper|S000048548}} PMID 1703236</ref><ref name='S000075094'>Muhlenhoff U, et al. (2003) A specific role of the yeast mitochondrial carriers MRS3/4p in mitochondrial iron acquisition under iron-limiting conditions. J Biol Chem 278(42):40612-20 {{SGDpaper|S000075094}} PMID 12902335</ref><ref name='S000129711'>Froschauer EM, et al. (2009) The yeast mitochondrial carrier proteins Mrs3p/Mrs4p mediate iron transport across the inner mitochondrial membrane. Biochim Biophys Acta
  {{SGDpaper|S000075094}} PMID 12902335</ref>
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  {{SGDpaper|S000129711}} PMID 19285482</ref>
 
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Revision as of 13:05, 31 March 2009

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Systematic name YKR052C
Gene name MRS4
Aliases
Feature type ORF, Verified
Coordinates Chr XI:533106..532192
Primary SGDID S000001760


Description of YKR052C: Iron transporter that mediates Fe2+ transport across the inner mitochondrial membrane; mitochondrial carrier family member, similar to and functionally redundant with Mrs3p; active under low-iron conditions; may transport other cations[1][2][3]




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References

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  1. Wiesenberger G, et al. (1991) MRS3 and MRS4, two suppressors of mtRNA splicing defects in yeast, are new members of the mitochondrial carrier family. J Mol Biol 217(1):23-37 SGD PMID 1703236
  2. Muhlenhoff U, et al. (2003) A specific role of the yeast mitochondrial carriers MRS3/4p in mitochondrial iron acquisition under iron-limiting conditions. J Biol Chem 278(42):40612-20 SGD PMID 12902335
  3. Froschauer EM, et al. (2009) The yeast mitochondrial carrier proteins Mrs3p/Mrs4p mediate iron transport across the inner mitochondrial membrane. Biochim Biophys Acta SGD PMID 19285482

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