Difference between revisions of "YOR124C"
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| − | '''Description of YOR124C:''' Ubiquitin-specific protease that removes ubiquitin from ubiquitinated proteins | + | '''Description of YOR124C:''' Ubiquitin-specific protease that removes ubiquitin from ubiquitinated proteins; interacts with Rsp5p and is required for MVB sorting of membrane proteins; can cleave polyubiquitin and has isopeptidase activity<ref name='S000129012'>Lam MH, et al. (2009) Interaction of the Deubiquitinating Enzyme Ubp2 and the E3 Ligase Rsp5 Is Required for Transporter/Receptor Sorting in the Multivesicular Body Pathway. PLoS ONE 4(1):e4259 {{SGDpaper|S000129012}} PMID 19165343</ref><ref name='S000052610'>Layfield R, et al. (1999) Chemically synthesized ubiquitin extension proteins detect distinct catalytic capacities of deubiquitinating enzymes. Anal Biochem 274(1):40-9 {{SGDpaper|S000052610}} PMID 10527495</ref><ref name='S000051210'>Baker RT, et al. (1992) Ubiquitin-specific proteases of Saccharomyces cerevisiae. Cloning of UBP2 and UBP3, and functional analysis of the UBP gene family. J Biol Chem 267(32):23364-75 |
{{SGDpaper|S000051210}} PMID 1429680</ref> | {{SGDpaper|S000051210}} PMID 1429680</ref> | ||
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Revision as of 13:05, 27 February 2009
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| Systematic name | YOR124C |
| Gene name | UBP2 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:558643..554825 |
| Primary SGDID | S000005650 |
Description of YOR124C: Ubiquitin-specific protease that removes ubiquitin from ubiquitinated proteins; interacts with Rsp5p and is required for MVB sorting of membrane proteins; can cleave polyubiquitin and has isopeptidase activity[1][2][3]
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References
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- ↑ Lam MH, et al. (2009) Interaction of the Deubiquitinating Enzyme Ubp2 and the E3 Ligase Rsp5 Is Required for Transporter/Receptor Sorting in the Multivesicular Body Pathway. PLoS ONE 4(1):e4259 SGD PMID 19165343
- ↑ Layfield R, et al. (1999) Chemically synthesized ubiquitin extension proteins detect distinct catalytic capacities of deubiquitinating enzymes. Anal Biochem 274(1):40-9 SGD PMID 10527495
- ↑ Baker RT, et al. (1992) Ubiquitin-specific proteases of Saccharomyces cerevisiae. Cloning of UBP2 and UBP3, and functional analysis of the UBP gene family. J Biol Chem 267(32):23364-75 SGD PMID 1429680
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