Difference between revisions of "YPR185W"

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'''Description of YPR185W:''' Phosphorylated protein that interacts with Vac8p, required for the cytoplasm-to-vacuole targeting (Cvt) pathway and autophagy<ref name='S000054987'>Scott SV, et al. (2000) Apg13p and Vac8p are part of a complex of phosphoproteins that are required for cytoplasm to vacuole targeting. J Biol Chem 275(33):25840-9 {{SGDpaper|S000054987}} PMID 10837477</ref><ref name='S000046726'>Funakoshi T, et al. (1997) Analyses of APG13 gene involved in autophagy in yeast, Saccharomyces cerevisiae. Gene 192(2):207-13
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'''Description of YPR185W:''' Regulatory subunit of the Atg1p signaling complex; stimulates Atg1p kinase activity; required for vesicle formation during autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; involved in Atg9p, Atg23p, and Atg27p cycling<ref name='S000080939'>Kabeya Y, et al. (2005) Atg17 functions in cooperation with Atg1 and Atg13 in yeast autophagy. Mol Biol Cell 16(5):2544-53 {{SGDpaper|S000080939}} PMID 15743910</ref><ref name='S000074945'>Reggiori F, et al. (2004) The Atg1-Atg13 complex regulates Atg9 and Atg23 retrieval transport from the pre-autophagosomal structure. Dev Cell 6(1):79-90 {{SGDpaper|S000074945}} PMID 14723849</ref><ref name='S000054987'>Scott SV, et al. (2000) Apg13p and Vac8p are part of a complex of phosphoproteins that are required for cytoplasm to vacuole targeting. J Biol Chem 275(33):25840-9 {{SGDpaper|S000054987}} PMID 10837477</ref><ref name='S000046726'>Funakoshi T, et al. (1997) Analyses of APG13 gene involved in autophagy in yeast, Saccharomyces cerevisiae. Gene 192(2):207-13
 
  {{SGDpaper|S000046726}} PMID 9224892</ref>
 
  {{SGDpaper|S000046726}} PMID 9224892</ref>
 
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Revision as of 06:21, 26 February 2009

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Systematic name YPR185W
Gene name ATG13
Aliases APG13
Feature type ORF, Verified
Coordinates Chr XVI:907214..909430
Primary SGDID S000006389


Description of YPR185W: Regulatory subunit of the Atg1p signaling complex; stimulates Atg1p kinase activity; required for vesicle formation during autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; involved in Atg9p, Atg23p, and Atg27p cycling[1][2][3][4]




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References

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  1. Kabeya Y, et al. (2005) Atg17 functions in cooperation with Atg1 and Atg13 in yeast autophagy. Mol Biol Cell 16(5):2544-53 SGD PMID 15743910
  2. Reggiori F, et al. (2004) The Atg1-Atg13 complex regulates Atg9 and Atg23 retrieval transport from the pre-autophagosomal structure. Dev Cell 6(1):79-90 SGD PMID 14723849
  3. Scott SV, et al. (2000) Apg13p and Vac8p are part of a complex of phosphoproteins that are required for cytoplasm to vacuole targeting. J Biol Chem 275(33):25840-9 SGD PMID 10837477
  4. Funakoshi T, et al. (1997) Analyses of APG13 gene involved in autophagy in yeast, Saccharomyces cerevisiae. Gene 192(2):207-13 SGD PMID 9224892

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