Difference between revisions of "YPR112C"

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'''Description of YPR112C:''' Essential conserved protein that associates with 35S precursor rRNA and is required for its initial processing at the A(0)-A(2) cleavage sites, shows partial nucleolar localization, contains five consensus RNA-binding domains<ref name='S000069866'>Jin SB, et al. (2002) Mrd1p is required for processing of pre-rRNA and for maintenance of steady-state levels of 40 S ribosomal subunits in yeast. J Biol Chem 277(21):18431-9
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'''Description of YPR112C:''' Essential conserved protein that is part of the 90S preribosome; required for production of 18S rRNA and small ribosomal subunit; contains five consensus RNA-binding domains<ref name='S000086600'>Grandi P, et al. (2002) 90S pre-ribosomes include the 35S pre-rRNA, the U3 snoRNP, and 40S subunit processing factors but predominantly lack 60S synthesis factors. Mol Cell 10(1):105-15 {{SGDpaper|S000086600}} PMID 12150911</ref><ref name='S000069866'>Jin SB, et al. (2002) Mrd1p is required for processing of pre-rRNA and for maintenance of steady-state levels of 40 S ribosomal subunits in yeast. J Biol Chem 277(21):18431-9
 
  {{SGDpaper|S000069866}} PMID 11884397</ref>
 
  {{SGDpaper|S000069866}} PMID 11884397</ref>
 
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Revision as of 06:21, 26 February 2009

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Systematic name YPR112C
Gene name MRD1
Aliases
Feature type ORF, Verified
Coordinates Chr XVI:751917..749254
Primary SGDID S000006316


Description of YPR112C: Essential conserved protein that is part of the 90S preribosome; required for production of 18S rRNA and small ribosomal subunit; contains five consensus RNA-binding domains[1][2]




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References

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  1. Grandi P, et al. (2002) 90S pre-ribosomes include the 35S pre-rRNA, the U3 snoRNP, and 40S subunit processing factors but predominantly lack 60S synthesis factors. Mol Cell 10(1):105-15 SGD PMID 12150911
  2. Jin SB, et al. (2002) Mrd1p is required for processing of pre-rRNA and for maintenance of steady-state levels of 40 S ribosomal subunits in yeast. J Biol Chem 277(21):18431-9 SGD PMID 11884397

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