Difference between revisions of "YPR001W"

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'''Description of YPR001W:''' Citrate synthase, catalyzes the condensation of acetyl coenzyme A and oxaloacetate to form citrate, mitochondrial isozyme involved in the TCA cycle<ref name='S000041688'>Jia YK, et al. (1997) The CIT3 gene of Saccharomyces cerevisiae encodes a second mitochondrial isoform of citrate synthase. Mol Microbiol 24(1):53-9
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'''Description of YPR001W:''' Dual specificity mitochondrial citrate and methylcitrate synthase; catalyzes the condensation of acetyl-CoA and oxaloacetate to form citrate and that of propionyl-CoA and oxaloacetate to form 2-methylcitrate<ref name='S000123009'>Graybill ER, et al. (2007) Functional comparison of citrate synthase isoforms from S. cerevisiae. Arch Biochem Biophys 465(1):26-37 {{SGDpaper|S000123009}} PMID 17570335</ref><ref name='S000041688'>Jia YK, et al. (1997) The CIT3 gene of Saccharomyces cerevisiae encodes a second mitochondrial isoform of citrate synthase. Mol Microbiol 24(1):53-9
 
  {{SGDpaper|S000041688}} PMID 9140965</ref>
 
  {{SGDpaper|S000041688}} PMID 9140965</ref>
 
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Revision as of 06:21, 26 February 2009

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Systematic name YPR001W
Gene name CIT3
Aliases
Feature type ORF, Verified
Coordinates Chr XVI:556374..557834
Primary SGDID S000006205


Description of YPR001W: Dual specificity mitochondrial citrate and methylcitrate synthase; catalyzes the condensation of acetyl-CoA and oxaloacetate to form citrate and that of propionyl-CoA and oxaloacetate to form 2-methylcitrate[1][2]




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DNA and RNA Details

Other DNA and RNA Details

Other Topic: expression

Specifically higher expression in carbon limited chemostat cultures versus carbon excess. [3] [4]





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References

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  1. Graybill ER, et al. (2007) Functional comparison of citrate synthase isoforms from S. cerevisiae. Arch Biochem Biophys 465(1):26-37 SGD PMID 17570335
  2. Jia YK, et al. (1997) The CIT3 gene of Saccharomyces cerevisiae encodes a second mitochondrial isoform of citrate synthase. Mol Microbiol 24(1):53-9 SGD PMID 9140965
  3. Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 SGD PMID 12414795
  4. submitted by Viktor Boer on 2003-07-25

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