Difference between revisions of "YPL157W"
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| − | '''Description of YPL157W:''' Trimethyl guanosine synthase, conserved nucleolar methyl transferase | + | '''Description of YPL157W:''' Trimethyl guanosine synthase, conserved nucleolar methyl transferase that converts the m(7)G cap structure of snRNAs, snoRNAs, and telomerase TLC1 RNA to m(2,2,7)G; also required for ribosome synthesis and nucleolar morphology<ref name='S000127970'>Franke J, et al. (2008) Hypermethylation of yeast telomerase RNA by the snRNA and snoRNA methyltransferase Tgs1. J Cell Sci 121(Pt 21):3553-60 {{SGDpaper|S000127970}} PMID 18840651</ref><ref name='S000077190'>Colau G, et al. (2004) The small nucle(ol)ar RNA cap trimethyltransferase is required for ribosome synthesis and intact nucleolar morphology. Mol Cell Biol 24(18):7976-86 {{SGDpaper|S000077190}} PMID 15340060</ref><ref name='S000070025'>Mouaikel J, et al. (2002) Hypermethylation of the cap structure of both yeast snRNAs and snoRNAs requires a conserved methyltransferase that is localized to the nucleolus. Mol Cell 9(4):891-901 |
{{SGDpaper|S000070025}} PMID 11983179</ref> | {{SGDpaper|S000070025}} PMID 11983179</ref> | ||
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Revision as of 07:21, 26 February 2009
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| Systematic name | YPL157W |
| Gene name | TGS1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XVI:254813..255760 |
| Primary SGDID | S000006078 |
Description of YPL157W: Trimethyl guanosine synthase, conserved nucleolar methyl transferase that converts the m(7)G cap structure of snRNAs, snoRNAs, and telomerase TLC1 RNA to m(2,2,7)G; also required for ribosome synthesis and nucleolar morphology[1][2][3]
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References
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- ↑ Franke J, et al. (2008) Hypermethylation of yeast telomerase RNA by the snRNA and snoRNA methyltransferase Tgs1. J Cell Sci 121(Pt 21):3553-60 SGD PMID 18840651
- ↑ Colau G, et al. (2004) The small nucle(ol)ar RNA cap trimethyltransferase is required for ribosome synthesis and intact nucleolar morphology. Mol Cell Biol 24(18):7976-86 SGD PMID 15340060
- ↑ Mouaikel J, et al. (2002) Hypermethylation of the cap structure of both yeast snRNAs and snoRNAs requires a conserved methyltransferase that is localized to the nucleolus. Mol Cell 9(4):891-901 SGD PMID 11983179
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