Difference between revisions of "YNR046W"
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| − | '''Description of YNR046W:''' Subunit of | + | '''Description of YNR046W:''' Subunit of tRNA methyltransferase (MTase) complexes in combination with Trm9p and Trm11p; subunit of complex with Mtq2p that methylates Sup45p (eRF1) in the ternary complex eRF1-eRF3-GTP; deletion confers resistance to zymocin<ref name='S000127221'>Studte P, et al. (2008) tRNA and protein methylase complexes mediate zymocin toxicity in yeast. Mol Microbiol 69(5):1266-77 {{SGDpaper|S000127221}} PMID 18657261</ref><ref name='S000118994'>Heurgue-Hamard V, et al. (2006) The Zinc Finger Protein Ynr046w Is Plurifunctional and a Component of the eRF1 Methyltransferase in Yeast. J Biol Chem 281(47):36140-8 {{SGDpaper|S000118994}} PMID 17008308</ref><ref name='S000081761'>Purushothaman SK, et al. (2005) Trm11p and Trm112p are both required for the formation of 2-methylguanosine at position 10 in yeast tRNA. Mol Cell Biol 25(11):4359-70 |
{{SGDpaper|S000081761}} PMID 15899842</ref> | {{SGDpaper|S000081761}} PMID 15899842</ref> | ||
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Revision as of 07:21, 26 February 2009
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| Systematic name | YNR046W |
| Gene name | TRM112 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XIV:707790..708197 |
| Primary SGDID | S000005329 |
Description of YNR046W: Subunit of tRNA methyltransferase (MTase) complexes in combination with Trm9p and Trm11p; subunit of complex with Mtq2p that methylates Sup45p (eRF1) in the ternary complex eRF1-eRF3-GTP; deletion confers resistance to zymocin[1][2][3]
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Contents
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References
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- ↑ Studte P, et al. (2008) tRNA and protein methylase complexes mediate zymocin toxicity in yeast. Mol Microbiol 69(5):1266-77 SGD PMID 18657261
- ↑ Heurgue-Hamard V, et al. (2006) The Zinc Finger Protein Ynr046w Is Plurifunctional and a Component of the eRF1 Methyltransferase in Yeast. J Biol Chem 281(47):36140-8 SGD PMID 17008308
- ↑ Purushothaman SK, et al. (2005) Trm11p and Trm112p are both required for the formation of 2-methylguanosine at position 10 in yeast tRNA. Mol Cell Biol 25(11):4359-70 SGD PMID 15899842
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