Difference between revisions of "YML014W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''TRM9 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''TRM9 ''
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''          ||'' ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''          ||''KTI1''
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''          || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''          || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
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'''Description of YML014W:''' tRNA methyltransferase, catalyzes the esterification of modified uridine nucleotides in tRNAs, creating 5-methylcarbonylmethyluridine in tRNA(Arg3) and 5-methylcarbonylmethyl-2-thiouridine in tRNA(Glu); may have a role in stress response<ref name='S000075253'>Kalhor HR and Clarke S (2003) Novel methyltransferase for modified uridine residues at the wobble position of tRNA. Mol Cell Biol 23(24):9283-92
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'''Description of YML014W:''' tRNA methyltransferase, catalyzes esterification of modified uridine nucleotides in tRNA(Arg3) and tRNA(Glu), likely as part of a complex with Trm112p; deletion confers resistance to zymocin<ref name='S000127221'>Studte P, et al. (2008) tRNA and protein methylase complexes mediate zymocin toxicity in yeast. Mol Microbiol 69(5):1266-77 {{SGDpaper|S000127221}} PMID 18657261</ref><ref name='S000113990'>Jablonowski D, et al. (2006) tRNAGlu wobble uridine methylation by Trm9 identifies Elongator's key role for zymocin-induced cell death in yeast. Mol Microbiol 59(2):677-88 {{SGDpaper|S000113990}} PMID 16390459</ref><ref name='S000075253'>Kalhor HR and Clarke S (2003) Novel methyltransferase for modified uridine residues at the wobble position of tRNA. Mol Cell Biol 23(24):9283-92
 
  {{SGDpaper|S000075253}} PMID 14645538</ref>
 
  {{SGDpaper|S000075253}} PMID 14645538</ref>
 
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Revision as of 07:21, 26 February 2009

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Systematic name YML014W
Gene name TRM9
Aliases KTI1
Feature type ORF, Verified
Coordinates Chr XIII:243225..244064
Primary SGDID S000004476


Description of YML014W: tRNA methyltransferase, catalyzes esterification of modified uridine nucleotides in tRNA(Arg3) and tRNA(Glu), likely as part of a complex with Trm112p; deletion confers resistance to zymocin[1][2][3]




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References

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  1. Studte P, et al. (2008) tRNA and protein methylase complexes mediate zymocin toxicity in yeast. Mol Microbiol 69(5):1266-77 SGD PMID 18657261
  2. Jablonowski D, et al. (2006) tRNAGlu wobble uridine methylation by Trm9 identifies Elongator's key role for zymocin-induced cell death in yeast. Mol Microbiol 59(2):677-88 SGD PMID 16390459
  3. Kalhor HR and Clarke S (2003) Novel methyltransferase for modified uridine residues at the wobble position of tRNA. Mol Cell Biol 23(24):9283-92 SGD PMID 14645538

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