Difference between revisions of "YLR304C"
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| − | '''Description of YLR304C:''' Aconitase, required for the tricarboxylic acid (TCA) cycle and also independently required for mitochondrial genome maintenance; component of the mitochondrial nucleoid; mutation leads to glutamate auxotrophy<ref name='S000080741'>Chen XJ, et al. (2005) Aconitase couples metabolic regulation to mitochondrial DNA maintenance. Science 307(5710):714-7 {{SGDpaper|S000080741}} PMID 15692048</ref><ref name='S000048212'>Gangloff SP, et al. (1990) Molecular cloning of the yeast mitochondrial aconitase gene (ACO1) and evidence of a synergistic regulation of expression by glucose plus glutamate. Mol Cell Biol 10(7):3551-61 | + | '''Description of YLR304C:''' Aconitase, required for the tricarboxylic acid (TCA) cycle and also independently required for mitochondrial genome maintenance; phosphorylated; component of the mitochondrial nucleoid; mutation leads to glutamate auxotrophy<ref name='S000123951'>Reinders J, et al. (2007) Profiling phosphoproteins of yeast mitochondria reveals a role of phosphorylation in assembly of the ATP synthase. Mol Cell Proteomics 6(11):1896-906 {{SGDpaper|S000123951}} PMID 17761666</ref><ref name='S000080741'>Chen XJ, et al. (2005) Aconitase couples metabolic regulation to mitochondrial DNA maintenance. Science 307(5710):714-7 {{SGDpaper|S000080741}} PMID 15692048</ref><ref name='S000048212'>Gangloff SP, et al. (1990) Molecular cloning of the yeast mitochondrial aconitase gene (ACO1) and evidence of a synergistic regulation of expression by glucose plus glutamate. Mol Cell Biol 10(7):3551-61 |
{{SGDpaper|S000048212}} PMID 1972545</ref> | {{SGDpaper|S000048212}} PMID 1972545</ref> | ||
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Revision as of 06:21, 26 February 2009
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| Systematic name | YLR304C |
| Gene name | ACO1 |
| Aliases | GLU1 |
| Feature type | ORF, Verified |
| Coordinates | Chr XII:737550..735214 |
| Primary SGDID | S000004295 |
Description of YLR304C: Aconitase, required for the tricarboxylic acid (TCA) cycle and also independently required for mitochondrial genome maintenance; phosphorylated; component of the mitochondrial nucleoid; mutation leads to glutamate auxotrophy[1][2][3]
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Protein Details
Other Protein Details
Other Topic: Regulated by the diauxic shift (glycerol)
Apart form the overall increase in mitochondrial protein mass after the diauxic shift this protein remains unchanged after the diauxic shift. [4] [5]
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References
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- ↑ Reinders J, et al. (2007) Profiling phosphoproteins of yeast mitochondria reveals a role of phosphorylation in assembly of the ATP synthase. Mol Cell Proteomics 6(11):1896-906 SGD PMID 17761666
- ↑ Chen XJ, et al. (2005) Aconitase couples metabolic regulation to mitochondrial DNA maintenance. Science 307(5710):714-7 SGD PMID 15692048
- ↑ Gangloff SP, et al. (1990) Molecular cloning of the yeast mitochondrial aconitase gene (ACO1) and evidence of a synergistic regulation of expression by glucose plus glutamate. Mol Cell Biol 10(7):3551-61 SGD PMID 1972545
- ↑ Ohlmeier S, et al. (2004) The yeast mitochondrial proteome, a study of fermentative and respiratory growth. J Biol Chem 279(6):3956-79 SGD PMID 14597615
- ↑ submitted by Steffen Ohlmeier on 2004-04-08
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