Difference between revisions of "YLR265C"
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| − | '''Description of YLR265C:''' Protein involved in regulation of nonhomologous end joining; repressed by MAT heterozygosity; | + | '''Description of YLR265C:''' Protein involved in regulation of nonhomologous end joining; interacts with DNA ligase IV components Dnl4p and Lif1p; repressed by MAT heterozygosity; regulates cellular distribution of Lif1p<ref name='S000123015'>Deshpande RA and Wilson TE (2007) Modes of interaction among yeast Nej1, Lif1 and Dnl4 proteins and comparison to human XLF, XRCC4 and Lig4. DNA Repair (Amst) 6(10):1507-16 {{SGDpaper|S000123015}} PMID 17567543</ref><ref name='S000069053'>Kegel A, et al. (2001) Nej1p, a cell type-specific regulator of nonhomologous end joining in yeast. Curr Biol 11(20):1611-7 {{SGDpaper|S000069053}} PMID 11676923</ref><ref name='S000067487'>Valencia M, et al. (2001) NEJ1 controls non-homologous end joining in Saccharomyces cerevisiae. Nature 414(6864):666-9 {{SGDpaper|S000067487}} PMID 11740566</ref><ref name='S000066210'>Frank-Vaillant M and Marcand S (2001) NHEJ regulation by mating type is exercised through a novel protein, Lif2p, essential to the ligase IV pathway. Genes Dev 15(22):3005-12 |
{{SGDpaper|S000066210}} PMID 11711435</ref> | {{SGDpaper|S000066210}} PMID 11711435</ref> | ||
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Revision as of 07:21, 26 February 2009
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| Systematic name | YLR265C |
| Gene name | NEJ1 |
| Aliases | LIF2 |
| Feature type | ORF, Verified |
| Coordinates | Chr XII:675457..674429 |
| Primary SGDID | S000004255 |
Description of YLR265C: Protein involved in regulation of nonhomologous end joining; interacts with DNA ligase IV components Dnl4p and Lif1p; repressed by MAT heterozygosity; regulates cellular distribution of Lif1p[1][2][3][4]
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References
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- ↑ Deshpande RA and Wilson TE (2007) Modes of interaction among yeast Nej1, Lif1 and Dnl4 proteins and comparison to human XLF, XRCC4 and Lig4. DNA Repair (Amst) 6(10):1507-16 SGD PMID 17567543
- ↑ Kegel A, et al. (2001) Nej1p, a cell type-specific regulator of nonhomologous end joining in yeast. Curr Biol 11(20):1611-7 SGD PMID 11676923
- ↑ Valencia M, et al. (2001) NEJ1 controls non-homologous end joining in Saccharomyces cerevisiae. Nature 414(6864):666-9 SGD PMID 11740566
- ↑ Frank-Vaillant M and Marcand S (2001) NHEJ regulation by mating type is exercised through a novel protein, Lif2p, essential to the ligase IV pathway. Genes Dev 15(22):3005-12 SGD PMID 11711435
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