Difference between revisions of "YJL208C"

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'''Description of YJL208C:''' Major mitochondrial nuclease, has RNAse and DNA endo- and exonucleolytic activities; has roles in mitochondrial recombination, apoptosis and maintenance of polyploidy<ref name='S000122630'>Buttner S, et al. (2007) Depletion of endonuclease g selectively kills polyploid cells. Cell Cycle 6(9):1072-6 {{SGDpaper|S000122630}} PMID 17471024</ref><ref name='S000120511'>Buttner S, et al. (2007) Endonuclease g regulates budding yeast life and death. Mol Cell 25(2):233-46 {{SGDpaper|S000120511}} PMID 17244531</ref><ref name='S000057053'>Dake E, et al. (1988) Purification and properties of the major nuclease from mitochondria of Saccharomyces cerevisiae. J Biol Chem 263(16):7691-702 {{SGDpaper|S000057053}} PMID 3286639</ref><ref name='S000052577'>Zassenhaus HP and Denniger G (1994) Analysis of the role of the NUC1 endo/exonuclease in yeast mitochondrial DNA recombination. Curr Genet 25(2):142-9 {{SGDpaper|S000052577}} PMID 8087883</ref><ref name='S000045493'>Vincent RD, et al. (1988) Sequence and expression of NUC1, the gene encoding the mitochondrial nuclease in Saccharomyces cerevisiae. Nucleic Acids Res 16(8):3297-312
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'''Description of YJL208C:''' Major mitochondrial nuclease, has RNAse and DNA endo- and exonucleolytic activities; has roles in mitochondrial recombination, apoptosis and maintenance of polyploidy<ref name='S000122630'>Buttner S, et al. (2007) Depletion of endonuclease G selectively kills polyploid cells. Cell Cycle 6(9):1072-6 {{SGDpaper|S000122630}} PMID 17471024</ref><ref name='S000120511'>Buttner S, et al. (2007) Endonuclease g regulates budding yeast life and death. Mol Cell 25(2):233-46 {{SGDpaper|S000120511}} PMID 17244531</ref><ref name='S000057053'>Dake E, et al. (1988) Purification and properties of the major nuclease from mitochondria of Saccharomyces cerevisiae. J Biol Chem 263(16):7691-702 {{SGDpaper|S000057053}} PMID 3286639</ref><ref name='S000052577'>Zassenhaus HP and Denniger G (1994) Analysis of the role of the NUC1 endo/exonuclease in yeast mitochondrial DNA recombination. Curr Genet 25(2):142-9 {{SGDpaper|S000052577}} PMID 8087883</ref><ref name='S000045493'>Vincent RD, et al. (1988) Sequence and expression of NUC1, the gene encoding the mitochondrial nuclease in Saccharomyces cerevisiae. Nucleic Acids Res 16(8):3297-312
 
  {{SGDpaper|S000045493}} PMID 2836792</ref>
 
  {{SGDpaper|S000045493}} PMID 2836792</ref>
 
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Revision as of 07:21, 26 February 2009

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Systematic name YJL208C
Gene name NUC1
Aliases
Feature type ORF, Verified
Coordinates Chr X:41183..40194
Primary SGDID S000003744


Description of YJL208C: Major mitochondrial nuclease, has RNAse and DNA endo- and exonucleolytic activities; has roles in mitochondrial recombination, apoptosis and maintenance of polyploidy[1][2][3][4][5]




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References

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  1. Buttner S, et al. (2007) Depletion of endonuclease G selectively kills polyploid cells. Cell Cycle 6(9):1072-6 SGD PMID 17471024
  2. Buttner S, et al. (2007) Endonuclease g regulates budding yeast life and death. Mol Cell 25(2):233-46 SGD PMID 17244531
  3. Dake E, et al. (1988) Purification and properties of the major nuclease from mitochondria of Saccharomyces cerevisiae. J Biol Chem 263(16):7691-702 SGD PMID 3286639
  4. Zassenhaus HP and Denniger G (1994) Analysis of the role of the NUC1 endo/exonuclease in yeast mitochondrial DNA recombination. Curr Genet 25(2):142-9 SGD PMID 8087883
  5. Vincent RD, et al. (1988) Sequence and expression of NUC1, the gene encoding the mitochondrial nuclease in Saccharomyces cerevisiae. Nucleic Acids Res 16(8):3297-312 SGD PMID 2836792

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