Difference between revisions of "YJL097W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''          ||'' ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''          ||'' ''
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''          || ORF, Uncharacterized[[Category:ORF]][[Category:ORF, Uncharacterized]]
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''          || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr X:245587..246240
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|nowrap| Chr X:245586..246239
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000003633
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000003633
 
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'''Description of YJL097W:''' Protein of unknown function; homolog of mammalian PTPLA; involved in sphingolipid biosynthesis, protein trafficking; required for cell viability<ref name='S000118289'>Yu L, et al. (2006) A survey of essential gene function in the yeast cell division cycle. Mol Biol Cell 17(11):4736-47 {{SGDpaper|S000118289}} PMID 16943325</ref><ref name='S000087084'>Schuldiner M, et al. (2005) Exploration of the function and organization of the yeast early secretory pathway through an epistatic miniarray profile. Cell 123(3):507-19
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'''Description of YJL097W:''' Essential 3-hydroxyacyl-CoA dehydratase of the ER membrane, involved in elongation of very long-chain fatty acids; evolutionarily conserved, similar to mammalian PTPLA and PTPLB; involved in sphingolipid biosynthesis and protein trafficking<ref name='S000125536'>Kihara A, et al. (2008) Membrane Topology and Essential Amino Acid Residues of Phs1, a 3-Hydroxyacyl-CoA Dehydratase Involved in Very Long-chain Fatty Acid Elongation. J Biol Chem 283(17):11199-209 {{SGDpaper|S000125536}} PMID 18272525</ref><ref name='S000118289'>Yu L, et al. (2006) A survey of essential gene function in the yeast cell division cycle. Mol Biol Cell 17(11):4736-47 {{SGDpaper|S000118289}} PMID 16943325</ref><ref name='S000087084'>Schuldiner M, et al. (2005) Exploration of the function and organization of the yeast early secretory pathway through an epistatic miniarray profile. Cell 123(3):507-19
 
  {{SGDpaper|S000087084}} PMID 16269340</ref>
 
  {{SGDpaper|S000087084}} PMID 16269340</ref>
 
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Revision as of 07:21, 26 February 2009

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Systematic name YJL097W
Gene name PHS1
Aliases
Feature type ORF, Verified
Coordinates Chr X:245586..246239
Primary SGDID S000003633


Description of YJL097W: Essential 3-hydroxyacyl-CoA dehydratase of the ER membrane, involved in elongation of very long-chain fatty acids; evolutionarily conserved, similar to mammalian PTPLA and PTPLB; involved in sphingolipid biosynthesis and protein trafficking[1][2][3]




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References

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  1. Kihara A, et al. (2008) Membrane Topology and Essential Amino Acid Residues of Phs1, a 3-Hydroxyacyl-CoA Dehydratase Involved in Very Long-chain Fatty Acid Elongation. J Biol Chem 283(17):11199-209 SGD PMID 18272525
  2. Yu L, et al. (2006) A survey of essential gene function in the yeast cell division cycle. Mol Biol Cell 17(11):4736-47 SGD PMID 16943325
  3. Schuldiner M, et al. (2005) Exploration of the function and organization of the yeast early secretory pathway through an epistatic miniarray profile. Cell 123(3):507-19 SGD PMID 16269340

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