Difference between revisions of "YGL236C"
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| − | '''Description of YGL236C:''' Mitochondrial protein, forms a heterodimer complex with Mss1p that performs the 5-carboxymethylaminomethyl modification of the wobble uridine base in mitochondrial tRNAs; required for respiration in paromomycin-resistant 15S rRNA mutants<ref name=' | + | '''Description of YGL236C:''' Mitochondrial protein, forms a heterodimer complex with Mss1p that performs the 5-carboxymethylaminomethyl modification of the wobble uridine base in mitochondrial tRNAs; required for respiration in paromomycin-resistant 15S rRNA mutants<ref name='S000080941'>Umeda N, et al. (2005) Mitochondria-specific RNA-modifying enzymes responsible for the biosynthesis of the wobble base in mitochondrial tRNAs. Implications for the molecular pathogenesis of human mitochondrial diseases. J Biol Chem 280(2):1613-24 {{SGDpaper|S000080941}} PMID 15509579</ref><ref name='S000053827'>Colby G, et al. (1998) MTO1 codes for a mitochondrial protein required for respiration in paromomycin-resistant mutants of Saccharomyces cerevisiae. J Biol Chem 273(43):27945-52 |
| − | {{SGDpaper| | + | {{SGDpaper|S000053827}} PMID 9774408</ref> |
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Revision as of 14:05, 16 January 2009
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| Systematic name | YGL236C |
| Gene name | MTO1 |
| Aliases | IPS1 |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:55796..53787 |
| Primary SGDID | S000003205 |
Description of YGL236C: Mitochondrial protein, forms a heterodimer complex with Mss1p that performs the 5-carboxymethylaminomethyl modification of the wobble uridine base in mitochondrial tRNAs; required for respiration in paromomycin-resistant 15S rRNA mutants[1][2]
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References
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- Jump up ↑ Umeda N, et al. (2005) Mitochondria-specific RNA-modifying enzymes responsible for the biosynthesis of the wobble base in mitochondrial tRNAs. Implications for the molecular pathogenesis of human mitochondrial diseases. J Biol Chem 280(2):1613-24 SGD PMID 15509579
- Jump up ↑ Colby G, et al. (1998) MTO1 codes for a mitochondrial protein required for respiration in paromomycin-resistant mutants of Saccharomyces cerevisiae. J Biol Chem 273(43):27945-52 SGD PMID 9774408
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