Difference between revisions of "YDR285W"

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'''Description of YDR285W:''' Transverse filament protein of the synaptonemal complex; required for normal levels of meiotic recombination and pairing between homologous chromosome during meiosis; potential Cdc28p substrate<ref name='S000047269'>Dong H and Roeder GS (2000) Organization of the yeast Zip1 protein within the central region of the synaptonemal complex. J Cell Biol 148(3):417-26 {{SGDpaper|S000047269}} PMID 10662769</ref><ref name='S000065797'>Storlazzi A, et al. (1996) Synaptonemal complex (SC) component Zip1 plays a role in meiotic recombination independent of SC polymerization along the chromosomes. Proc Natl Acad Sci U S A 93(17):9043-8 {{SGDpaper|S000065797}} PMID 8799151</ref><ref name='S000074306'>Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 {{SGDpaper|S000074306}} PMID 14574415</ref><ref name='S000081732'>Tsubouchi T and Roeder GS (2005) A synaptonemal complex protein promotes homology-independent centromere coupling. Science 308(5723):870-3
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'''Description of YDR285W:''' Transverse filament protein of the synaptonemal complex; required for normal levels of meiotic recombination and pairing between homologous chromosome during meiosis; potential Cdc28p substrate<ref name='S000081732'>Tsubouchi T and Roeder GS (2005) A synaptonemal complex protein promotes homology-independent centromere coupling. Science 308(5723):870-3 {{SGDpaper|S000081732}} PMID 15879219</ref><ref name='S000074306'>Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 {{SGDpaper|S000074306}} PMID 14574415</ref><ref name='S000065797'>Storlazzi A, et al. (1996) Synaptonemal complex (SC) component Zip1 plays a role in meiotic recombination independent of SC polymerization along the chromosomes. Proc Natl Acad Sci U S A 93(17):9043-8 {{SGDpaper|S000065797}} PMID 8799151</ref><ref name='S000047269'>Dong H and Roeder GS (2000) Organization of the yeast Zip1 protein within the central region of the synaptonemal complex. J Cell Biol 148(3):417-26
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  {{SGDpaper|S000047269}} PMID 10662769</ref>
 
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Revision as of 13:05, 16 January 2009

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Systematic name YDR285W
Gene name ZIP1
Aliases
Feature type ORF, Verified
Coordinates Chr IV:1032433..1035060
Primary SGDID S000002693


Description of YDR285W: Transverse filament protein of the synaptonemal complex; required for normal levels of meiotic recombination and pairing between homologous chromosome during meiosis; potential Cdc28p substrate[1][2][3][4]




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Protein Details

Protein Modification

Modification(s): Phosphorylation

Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [2] [5]





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References

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  1. Tsubouchi T and Roeder GS (2005) A synaptonemal complex protein promotes homology-independent centromere coupling. Science 308(5723):870-3 SGD PMID 15879219
  2. 2.0 2.1 Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
  3. Storlazzi A, et al. (1996) Synaptonemal complex (SC) component Zip1 plays a role in meiotic recombination independent of SC polymerization along the chromosomes. Proc Natl Acad Sci U S A 93(17):9043-8 SGD PMID 8799151
  4. Dong H and Roeder GS (2000) Organization of the yeast Zip1 protein within the central region of the synaptonemal complex. J Cell Biol 148(3):417-26 SGD PMID 10662769
  5. submitted by Jeff Ubersax on 2004-01-21

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