Difference between revisions of "YDL113C"
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− | '''Description of YDL113C:''' Sorting nexin family member required for the cytoplasm-to-vacuole targeting (Cvt) pathway and for endosomal sorting; has a Phox homology domain that binds phosphatidylinositol-3-phosphate; interacts with Snx4p; potential Cdc28p substrate<ref name=' | + | '''Description of YDL113C:''' Sorting nexin family member required for the cytoplasm-to-vacuole targeting (Cvt) pathway and for endosomal sorting; has a Phox homology domain that binds phosphatidylinositol-3-phosphate; interacts with Snx4p; potential Cdc28p substrate<ref name='S000074306'>Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 {{SGDpaper|S000074306}} PMID 14574415</ref><ref name='S000072811'>Hettema EH, et al. (2003) Retromer and the sorting nexins Snx4/41/42 mediate distinct retrieval pathways from yeast endosomes. EMBO J 22(3):548-57 {{SGDpaper|S000072811}} PMID 12554655</ref><ref name='S000070289'>Nice DC, et al. (2002) Cooperative binding of the cytoplasm to vacuole targeting pathway proteins, Cvt13 and Cvt20, to phosphatidylinositol 3-phosphate at the pre-autophagosomal structure is required for selective autophagy. J Biol Chem 277(33):30198-207 |
− | {{SGDpaper| | + | {{SGDpaper|S000070289}} PMID 12048214</ref> |
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Revision as of 14:05, 16 January 2009
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Systematic name | YDL113C |
Gene name | ATG20 |
Aliases | CVT20, SNX42 |
Feature type | ORF, Verified |
Coordinates | Chr IV:258555..256633 |
Primary SGDID | S000002271 |
Description of YDL113C: Sorting nexin family member required for the cytoplasm-to-vacuole targeting (Cvt) pathway and for endosomal sorting; has a Phox homology domain that binds phosphatidylinositol-3-phosphate; interacts with Snx4p; potential Cdc28p substrate[1][2][3]
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Protein Details
Protein Modification
Modification(s): Phosphorylation
Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [1] [4]
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References
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- ↑ 1.0 1.1 Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
- ↑ Hettema EH, et al. (2003) Retromer and the sorting nexins Snx4/41/42 mediate distinct retrieval pathways from yeast endosomes. EMBO J 22(3):548-57 SGD PMID 12554655
- ↑ Nice DC, et al. (2002) Cooperative binding of the cytoplasm to vacuole targeting pathway proteins, Cvt13 and Cvt20, to phosphatidylinositol 3-phosphate at the pre-autophagosomal structure is required for selective autophagy. J Biol Chem 277(33):30198-207 SGD PMID 12048214
- ↑ submitted by Jeff Ubersax on 2004-01-21
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