Difference between revisions of "YER154W"

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'''Description of YER154W:''' Mitochondrial inner membrane insertase, mediates the insertion of both mitochondrial- and nuclear-encoded proteins from the matrix into the inner membrane, interacts with mitochondrial ribosomes; conserved from bacteria to animals<ref name='S000050616'>Bonnefoy N, et al. (1994) Cloning of a human gene involved in cytochrome oxidase assembly by functional complementation of an oxa1- mutation in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 91(25):11978-82 {{SGDpaper|S000050616}} PMID 7991568</ref><ref name='S000075521'>Jia L, et al. (2003) Yeast Oxa1 interacts with mitochondrial ribosomes: the importance of the C-terminal region of Oxa1. EMBO J 22(24):6438-47 {{SGDpaper|S000075521}} PMID 14657017</ref><ref name='S000075522'>Szyrach G, et al. (2003) Ribosome binding to the Oxa1 complex facilitates co-translational protein insertion in mitochondria. EMBO J 22(24):6448-57
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'''Description of YER154W:''' Mitochondrial inner membrane insertase, mediates the insertion of both mitochondrial- and nuclear-encoded proteins from the matrix into the inner membrane, interacts with mitochondrial ribosomes; conserved from bacteria to animals<ref name='S000075522'>Szyrach G, et al. (2003) Ribosome binding to the Oxa1 complex facilitates co-translational protein insertion in mitochondria. EMBO J 22(24):6448-57 {{SGDpaper|S000075522}} PMID 14657018</ref><ref name='S000075521'>Jia L, et al. (2003) Yeast Oxa1 interacts with mitochondrial ribosomes: the importance of the C-terminal region of Oxa1. EMBO J 22(24):6438-47 {{SGDpaper|S000075521}} PMID 14657017</ref><ref name='S000050616'>Bonnefoy N, et al. (1994) Cloning of a human gene involved in cytochrome oxidase assembly by functional complementation of an oxa1- mutation in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 91(25):11978-82
  {{SGDpaper|S000075522}} PMID 14657018</ref>
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  {{SGDpaper|S000050616}} PMID 7991568</ref>
 
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Revision as of 14:05, 16 January 2009

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Systematic name YER154W
Gene name OXA1
Aliases PET1402
Feature type ORF, Verified
Coordinates Chr V:475015..476223
Primary SGDID S000000956


Description of YER154W: Mitochondrial inner membrane insertase, mediates the insertion of both mitochondrial- and nuclear-encoded proteins from the matrix into the inner membrane, interacts with mitochondrial ribosomes; conserved from bacteria to animals[1][2][3]




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References

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  1. Szyrach G, et al. (2003) Ribosome binding to the Oxa1 complex facilitates co-translational protein insertion in mitochondria. EMBO J 22(24):6448-57 SGD PMID 14657018
  2. Jia L, et al. (2003) Yeast Oxa1 interacts with mitochondrial ribosomes: the importance of the C-terminal region of Oxa1. EMBO J 22(24):6438-47 SGD PMID 14657017
  3. Bonnefoy N, et al. (1994) Cloning of a human gene involved in cytochrome oxidase assembly by functional complementation of an oxa1- mutation in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 91(25):11978-82 SGD PMID 7991568

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