Difference between revisions of "YEL032W"
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| − | '''Description of YEL032W:''' Protein involved in DNA replication; component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex<ref name=' | + | '''Description of YEL032W:''' Protein involved in DNA replication; component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex<ref name='S000054742'>Yan H, et al. (1991) Mcm2 and Mcm3, two proteins important for ARS activity, are related in structure and function. Genes Dev 5(6):944-57 {{SGDpaper|S000054742}} PMID 2044961</ref><ref name='S000046283'>Whitebread LA and Dalton S (1995) Cdc54 belongs to the Cdc46/Mcm3 family of proteins which are essential for initiation of eukaryotic DNA replication. Gene 155(1):113-7 {{SGDpaper|S000046283}} PMID 7698653</ref><ref name='S000040243'>Homesley L, et al. (2000) Mcm10 and the MCM2-7 complex interact to initiate DNA synthesis and to release replication factors from origins. Genes Dev 14(8):913-26 |
| − | {{SGDpaper| | + | {{SGDpaper|S000040243}} PMID 10783164</ref> |
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Revision as of 13:05, 16 January 2009
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| Systematic name | YEL032W |
| Gene name | MCM3 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr V:86937..89852 |
| Primary SGDID | S000000758 |
Description of YEL032W: Protein involved in DNA replication; component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex[1][2][3]
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Community Commentary
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Protein Details
Protein Modification
Modification(s): Phosphorylation
Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [4] [5]
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References
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- ↑ Yan H, et al. (1991) Mcm2 and Mcm3, two proteins important for ARS activity, are related in structure and function. Genes Dev 5(6):944-57 SGD PMID 2044961
- ↑ Whitebread LA and Dalton S (1995) Cdc54 belongs to the Cdc46/Mcm3 family of proteins which are essential for initiation of eukaryotic DNA replication. Gene 155(1):113-7 SGD PMID 7698653
- ↑ Homesley L, et al. (2000) Mcm10 and the MCM2-7 complex interact to initiate DNA synthesis and to release replication factors from origins. Genes Dev 14(8):913-26 SGD PMID 10783164
- ↑ Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
- ↑ submitted by Jeff Ubersax on 2004-01-27
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