Difference between revisions of "YDR510W"
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| − | '''Description of YDR510W:''' Ubiquitin-like protein of the SUMO family, conjugated to lysine residues of target proteins; regulates chromatid cohesion, chromosome segregation, APC-mediated proteolysis, DNA replication and septin ring dynamics; phosphorylated at Ser2<ref name=' | + | '''Description of YDR510W:''' Ubiquitin-like protein of the SUMO family, conjugated to lysine residues of target proteins; regulates chromatid cohesion, chromosome segregation, APC-mediated proteolysis, DNA replication and septin ring dynamics; phosphorylated at Ser2<ref name='S000039641'>Johnson ES and Blobel G (1999) Cell cycle-regulated attachment of the ubiquitin-related protein SUMO to the yeast septins. J Cell Biol 147(5):981-94 {{SGDpaper|S000039641}} PMID 10579719</ref><ref name='S000049722'>Takahashi Y, et al. (1999) Smt3, a SUMO-1 homolog, is conjugated to Cdc3, a component of septin rings at the mother-bud neck in budding yeast. Biochem Biophys Res Commun 259(3):582-7 {{SGDpaper|S000049722}} PMID 10364461</ref><ref name='S000066115'>Biggins S, et al. (2001) Genes involved in sister chromatid separation and segregation in the budding yeast Saccharomyces cerevisiae. Genetics 159(2):453-70 {{SGDpaper|S000066115}} PMID 11606525</ref><ref name='S000070282'>Bachant J, et al. (2002) The SUMO-1 isopeptidase Smt4 is linked to centromeric cohesion through SUMO-1 modification of DNA topoisomerase II. Mol Cell 9(6):1169-82 {{SGDpaper|S000070282}} PMID 12086615</ref><ref name='S000071479'>Hoege C, et al. (2002) RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO. Nature 419(6903):135-41 {{SGDpaper|S000071479}} PMID 12226657</ref><ref name='S000075766'>Dieckhoff P, et al. (2004) Smt3/SUMO and Ubc9 are required for efficient APC/C-mediated proteolysis in budding yeast. Mol Microbiol 51(5):1375-87 {{SGDpaper|S000075766}} PMID 14982631</ref><ref name='S000077724'>Stead K, et al. (2003) Pds5p regulates the maintenance of sister chromatid cohesion and is sumoylated to promote the dissolution of cohesion. J Cell Biol 163(4):729-41 {{SGDpaper|S000077724}} PMID 14623866</ref><ref name='S000127508'>Matic I, et al. (2008) Phosphorylation of SUMO-1 Occurs in Vivo and Is Conserved through Evolution. J Proteome Res 7(9):4050-4057 |
| − | {{SGDpaper| | + | {{SGDpaper|S000127508}} PMID 18707152</ref> |
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Revision as of 03:15, 19 December 2008
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| Systematic name | YDR510W |
| Gene name | SMT3 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:1469393..1469698 |
| Primary SGDID | S000002918 |
Description of YDR510W: Ubiquitin-like protein of the SUMO family, conjugated to lysine residues of target proteins; regulates chromatid cohesion, chromosome segregation, APC-mediated proteolysis, DNA replication and septin ring dynamics; phosphorylated at Ser2[1][2][3][4][5][6][7][8]
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References
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- ↑ Johnson ES and Blobel G (1999) Cell cycle-regulated attachment of the ubiquitin-related protein SUMO to the yeast septins. J Cell Biol 147(5):981-94 SGD PMID 10579719
- ↑ Takahashi Y, et al. (1999) Smt3, a SUMO-1 homolog, is conjugated to Cdc3, a component of septin rings at the mother-bud neck in budding yeast. Biochem Biophys Res Commun 259(3):582-7 SGD PMID 10364461
- ↑ Biggins S, et al. (2001) Genes involved in sister chromatid separation and segregation in the budding yeast Saccharomyces cerevisiae. Genetics 159(2):453-70 SGD PMID 11606525
- ↑ Bachant J, et al. (2002) The SUMO-1 isopeptidase Smt4 is linked to centromeric cohesion through SUMO-1 modification of DNA topoisomerase II. Mol Cell 9(6):1169-82 SGD PMID 12086615
- ↑ Hoege C, et al. (2002) RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO. Nature 419(6903):135-41 SGD PMID 12226657
- ↑ Dieckhoff P, et al. (2004) Smt3/SUMO and Ubc9 are required for efficient APC/C-mediated proteolysis in budding yeast. Mol Microbiol 51(5):1375-87 SGD PMID 14982631
- ↑ Stead K, et al. (2003) Pds5p regulates the maintenance of sister chromatid cohesion and is sumoylated to promote the dissolution of cohesion. J Cell Biol 163(4):729-41 SGD PMID 14623866
- ↑ Matic I, et al. (2008) Phosphorylation of SUMO-1 Occurs in Vivo and Is Conserved through Evolution. J Proteome Res 7(9):4050-4057 SGD PMID 18707152
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